{"id":"W3173471877","doi":"10.3390/jcm10132912","title":"Landscape of Preterm Birth Therapeutics and a Path Forward","year":2021,"lang":"en","type":"review","venue":"Journal of Clinical Medicine","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Alberta; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; Medical Research Council; Canadian Institutes of Health Research; University of Washington; Children's Health Research Institute; Women and Children's Health Research Institute; Stollery Children’s Hospital Foundation; National Institutes of Health; Children's Hospital Foundation; March of Dimes Foundation; Burroughs Wellcome Fund","keywords":"Medicine; Intensive care medicine; Tocolytic agent; Tocolytic; Adverse effect; Drug development; Drug; Pharmacology; Fetus; Pregnancy; Preterm labor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001288482,0.0006389642,0.001122944,0.002020956,0.0003917463,0.001555542,0.0007308832,0.001632853,0.004758733],"category_scores_gemma":[0.002139502,0.0002728114,0.0006332772,0.001713415,0.0005846457,0.002572767,0.0008160951,0.003006023,0.001664899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001016756,"about_ca_system_score_gemma":0.002441955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001181684,"about_ca_topic_score_gemma":0.002287409,"domain_scores_codex":[0.9996319,0.00008928243,0.00005201053,0.00005007908,0.0001370975,0.00003975168],"domain_scores_gemma":[0.9987603,0.0007285092,0.0001083818,0.00002812027,0.0003035295,0.00007117832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001151156,0.00009904789,0.0001716545,0.02159964,0.00008073976,0.0002195572,0.0001299809,0.0003831303,0.001114008,0.01193011,0.05263282,0.9115241],"study_design_scores_gemma":[0.00001698955,0.0001372447,0.0003752914,0.008275754,0.00008757386,0.0005566812,0.000089777,0.0001055596,0.0002427194,0.003773972,0.9863236,0.00001470074],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000822802,0.9973573,0.00008374379,0.00130467,0.0002846421,0.000003235563,0.00001453475,0.000007662847,0.0008619323],"genre_scores_gemma":[0.0006507264,0.9975808,0.0002178235,0.0007727703,0.0002678812,0.000005836918,0.00002260417,0.000002309139,0.0004791925],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004758733,"threshold_uncertainty_score":0.01591957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1354738415376764,"score_gpt":0.4635601062242147,"score_spread":0.3280862646865383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}