{"id":"W3173471877","doi":"10.3390/jcm10132912","title":"Landscape of Preterm Birth Therapeutics and a Path Forward","year":2021,"lang":"en","type":"review","venue":"Journal of Clinical Medicine","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Alberta; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; Medical Research Council; Canadian Institutes of Health Research; University of Washington; Children's Health Research Institute; Women and Children's Health Research Institute; Stollery Children’s Hospital Foundation; National Institutes of Health; Children's Hospital Foundation; March of Dimes Foundation; Burroughs Wellcome Fund","keywords":"Medicine; Intensive care medicine; Tocolytic agent; Tocolytic; Adverse effect; Drug development; Drug; Pharmacology; Fetus; Pregnancy; Preterm labor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002046163,0.0003409429,0.006254203,0.0002504611,0.0000222009,0.000008537333,0.0002131435,0.0005391359,0.0002551955],"category_scores_gemma":[0.00230967,0.0001871926,0.001120369,0.000256971,0.0003307217,0.00005047368,0.00007067085,0.00150714,0.000001924063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001825713,"about_ca_system_score_gemma":0.0009321064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001323491,"about_ca_topic_score_gemma":6.170701e-7,"domain_scores_codex":[0.9945725,0.000378161,0.003866241,0.0002522669,0.0007003234,0.0002304646],"domain_scores_gemma":[0.9937137,0.00190021,0.002935799,0.000406798,0.0005133909,0.000530059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001580735,0.0001162198,0.002349309,0.01237707,0.001032691,0.0005265332,0.00006914859,6.373314e-9,5.019292e-7,0.00002270023,0.001665851,0.9816819],"study_design_scores_gemma":[0.003283555,0.004384694,0.000774677,0.08201426,0.005780182,0.003022721,0.00005918142,0.000004120238,6.388927e-7,0.00005992411,0.9004736,0.0001424449],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004576297,0.9959295,0.00005261296,0.0006526007,0.00116649,0.0002952341,0.00002229821,0.000007150509,0.001416471],"genre_scores_gemma":[0.0007274636,0.9947057,0.0004853005,0.000595091,0.003182641,0.000002947151,0.00002019699,0.00004254016,0.0002380848],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9815394,"threshold_uncertainty_score":0.7633491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1354738415376764,"score_gpt":0.4635601062242147,"score_spread":0.3280862646865383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}