{"id":"W3173818796","doi":"10.1002/stem.3422","title":"Sars-Cov-2 Infects an Upper Airway Model Derived from Induced Pluripotent Stem Cells","year":2021,"lang":"en","type":"article","venue":"Stem Cells","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; H2020 Marie Skłodowska-Curie Actions; Economic and Social Research Council; Horizon 2020 Framework Programme; Medical Research Council; Royal Society; Directorate for Biological Sciences; Medical Research Council Canada; National Institute for Health and Care Research; Biotechnology and Biological Sciences Research Council; Liverpool School of Tropical Medicine","keywords":"Biology; Respiratory epithelium; Induced pluripotent stem cell; Cell biology; In vivo; Airway; Epithelium; Mucus; Stem cell; Immunology; Lung; Embryonic stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003832882,0.0003940881,0.000704953,0.0001948421,0.0001628225,0.00007968472,0.0002721728,0.0003644747,0.0001931178],"category_scores_gemma":[0.00002138815,0.0003674748,0.0001944112,0.0004049468,0.00007735068,0.000237503,0.000276855,0.0008249294,0.001187802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004108906,"about_ca_system_score_gemma":0.001698245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003003621,"about_ca_topic_score_gemma":0.000167607,"domain_scores_codex":[0.9959399,0.0003749439,0.0006422302,0.0009639797,0.001127383,0.0009515642],"domain_scores_gemma":[0.9973303,0.0002160161,0.0001444546,0.001142969,0.0004679448,0.0006982858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002239395,0.0002921098,0.0001815464,0.0004512305,0.0000668905,0.0006480442,0.0006686735,0.00005423574,0.9523109,0.00001606897,0.0004424286,0.04464398],"study_design_scores_gemma":[0.002194801,0.0004326065,0.0002323245,0.0002297664,0.00005315624,0.00001184792,0.0003768597,0.008132161,0.9791527,0.00003861833,0.008821297,0.0003238303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943219,0.001695952,0.0003893979,0.0004095158,0.0005361789,0.001001803,0.000102718,0.0001445644,0.001397965],"genre_scores_gemma":[0.9926579,0.0002368332,0.0006548832,0.003519673,0.0002670202,0.00006416788,0.00003265491,0.0001222748,0.002444586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04432015,"threshold_uncertainty_score":0.9998777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09261673970875794,"score_gpt":0.3518168190944572,"score_spread":0.2592000793856992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}