{"id":"W3173868070","doi":"10.1083/jcb.202005072","title":"Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes","year":2021,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Government of Ontario; Ryerson University","keywords":"Phagosome; Phagocytosis; Cell biology; Lysosome; Endocytosis; Biology; Exocytosis; Chemistry; Membrane; Biochemistry; Cell; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568077,0.0001907562,0.0003308816,0.0003580074,0.0003380049,0.0007355069,0.0002600788,0.0004378406,0.0004233959],"category_scores_gemma":[0.0001965659,0.000156784,0.0003223483,0.0001316766,0.0003442914,0.0004824292,0.0005514364,0.0005478066,0.000291189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004379773,"about_ca_system_score_gemma":0.0005031737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006855544,"about_ca_topic_score_gemma":0.0007196798,"domain_scores_codex":[0.9997726,0.00003484705,0.00002100703,0.00004020582,0.00006411358,0.00006727477],"domain_scores_gemma":[0.9998131,0.00001574784,0.00003869074,0.00003259113,0.00003875123,0.00006111401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001242054,0.00001786781,0.0007783772,0.00004081656,0.000006411588,0.0001690802,0.00003758569,0.00006455319,0.9963947,0.0004408924,0.00006659604,0.00185893],"study_design_scores_gemma":[0.00001536297,0.0001650164,0.01544923,0.00001759181,0.00001484117,0.0007959117,0.0001093715,0.001463211,0.9773254,0.0003374589,0.004294403,0.00001213533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846015,0.005737695,0.007652453,0.0003035743,0.00003324762,0.00002496456,0.0001333782,0.0001388178,0.001374329],"genre_scores_gemma":[0.9938983,0.001010584,0.002855478,0.00006929381,0.00001295963,0.00001533886,0.0001051535,0.00002082461,0.002012102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007355069,"threshold_uncertainty_score":0.003177762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191034436541879,"score_gpt":0.2274287804140905,"score_spread":0.2083253367599026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}