{"id":"W3173878348","doi":"10.1111/bjd.20595","title":"Long‐term efficacy and safety of risankizumab for the treatment of moderate‐to‐severe plaque psoriasis: interim analysis of the LIMMitless open‐label extension trial beyond 3 years of follow‐up","year":2021,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"","keywords":"Psoriasis Area and Severity Index; Medicine; Dermatology Life Quality Index; Psoriasis; Discontinuation; Adverse effect; Internal medicine; Randomized controlled trial; Quality of life (healthcare); Dermatology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01060093,0.001141978,0.003137248,0.000506083,0.0005620179,0.001820666,0.0009007981,0.001386613,0.003675483],"category_scores_gemma":[0.005708153,0.0004387117,0.003954607,0.0004982103,0.0008327751,0.001531203,0.0007664625,0.002609179,0.0007173028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005831017,"about_ca_system_score_gemma":0.001161036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00033424,"about_ca_topic_score_gemma":0.0005661365,"domain_scores_codex":[0.997206,0.001495454,0.000184484,0.0003477704,0.0003676965,0.0003985355],"domain_scores_gemma":[0.9949255,0.001621433,0.001481939,0.0008666505,0.0004459728,0.0006584806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9604674,0.003837283,0.00861232,0.0004480416,0.003317444,0.00008493021,0.0000878072,0.0009155395,0.00232309,0.000130445,0.001823151,0.01795248],"study_design_scores_gemma":[0.6123328,0.2668853,0.09556701,0.0002166315,0.01209478,0.0003559808,0.0001125836,0.00353899,0.003854451,0.0008394668,0.004097439,0.0001045131],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860887,0.004615397,0.00121282,0.0003582936,0.0001727368,0.001283199,0.00334562,0.0001213275,0.002802009],"genre_scores_gemma":[0.9903163,0.0006838482,0.001137079,0.000451411,0.0001705144,0.001560217,0.004120252,0.00002639897,0.001534058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01060093,"threshold_uncertainty_score":0.05606371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03393482954166807,"score_gpt":0.2914853224965989,"score_spread":0.2575504929549308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}