{"id":"W3173926394","doi":"10.1096/fasebj.27.1_supplement.1031.20","title":"Determinants of physical and functional coupling between Thromboxane A2 receptor and Gαq","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Manitoba Health Research Council","keywords":"G protein-coupled receptor; Heterotrimeric G protein; G protein; Receptor; Chemistry; Cysteine; Thromboxane receptor; Thromboxane A2; Biochemistry; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000192183,0.0002462092,0.0001598636,0.0001134008,0.0001403215,0.0002097263,0.0002669331,0.0002194799,0.001441547],"category_scores_gemma":[0.000389452,0.0001193432,0.0001639964,0.00007303784,0.0003248283,0.0001526588,0.0002621351,0.0003443808,0.0002951051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002952261,"about_ca_system_score_gemma":0.0001659767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007304035,"about_ca_topic_score_gemma":0.0005770708,"domain_scores_codex":[0.9998134,0.00007301192,0.00001213325,0.00002905696,0.00003947008,0.00003295032],"domain_scores_gemma":[0.9997335,0.00008066569,0.00008170658,0.00002394269,0.00002284225,0.00005720152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001248022,0.0000188396,0.0007216735,0.00001473856,0.000007221416,0.0001375956,0.00001234582,0.0001598408,0.9979998,0.0002916803,0.00002251732,0.0004888212],"study_design_scores_gemma":[0.0001181952,0.0004954498,0.03655184,0.00002224839,0.00004785316,0.001556433,0.0001347246,0.006011148,0.9503715,0.0004772689,0.004199173,0.00001415454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982828,0.0001695471,0.0009350808,0.00006743609,0.000006153969,0.0000066725,0.00004321251,0.000006700564,0.000482338],"genre_scores_gemma":[0.9988784,0.00007009899,0.0005364276,0.00002433746,0.000002973271,0.000007661363,0.00009437952,0.000004420428,0.0003811026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001441547,"threshold_uncertainty_score":0.004822433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613908844696178,"score_gpt":0.2438571228908329,"score_spread":0.2277180344438712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}