{"id":"W3173931092","doi":"10.1096/fasebj.27.1_supplement.1118.30","title":"INCREASING LEPTIN SENSITIVITY VIA PTP1B DELETION DOES NOT INCREASE BLOOD PRESSURE THROUGH AN INCREASED SYMPATHETIC TONE IN MICE ON A BALB/C BACKGROUND","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Internal medicine; Endocrinology; Leptin; Phenylephrine; Medicine; Blood pressure; BALB/c; Stimulation; Adrenergic; Chemistry; Receptor; Immune system; Immunology; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004762922,0.0009393714,0.0006928206,0.001174614,0.0005288122,0.0009641195,0.0007846293,0.0009793558,0.005961713],"category_scores_gemma":[0.0003773076,0.0006774986,0.0007340792,0.0004200483,0.0008184634,0.0005930081,0.0005482641,0.00330858,0.001140783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005189669,"about_ca_system_score_gemma":0.000495221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001619423,"about_ca_topic_score_gemma":0.002887043,"domain_scores_codex":[0.9990748,0.00008932089,0.000118441,0.0002631137,0.0002583001,0.0001959878],"domain_scores_gemma":[0.9987109,0.0000812451,0.0004016687,0.0001518661,0.0000877051,0.000566644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006520619,0.0001550168,0.0004083372,0.00005079862,0.0000184904,0.00006314536,0.00003010861,0.00005156463,0.9973557,0.0001440296,0.0000756439,0.0009951304],"study_design_scores_gemma":[0.000390633,0.002564508,0.03700697,0.0001247736,0.000168106,0.0009455578,0.0002126165,0.001688308,0.9519926,0.0002966662,0.004556281,0.00005291571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900796,0.001374632,0.003037815,0.0004811277,0.0001500057,0.00008771032,0.002237438,0.000223826,0.002327897],"genre_scores_gemma":[0.9695024,0.002311382,0.007977769,0.0005442708,0.0001040874,0.0004538463,0.003094175,0.0003551111,0.01565692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005961713,"threshold_uncertainty_score":0.01994395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227171572379362,"score_gpt":0.2628081052969328,"score_spread":0.2405363895731392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}