{"id":"W3173945610","doi":"10.3390/vaccines9080852","title":"Cellular and Humoral Immunogenicity of a Candidate DNA Vaccine Expressing SARS-CoV-2 Spike Subunit 1","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Immunogenicity; Immunogen; Immune system; Virology; Antibody; Biology; DNA vaccination; Immunology; CD8; Immunization; Protein subunit; Humoral immunity; Monoclonal antibody; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002096743,0.0004532952,0.0002188221,0.0001866567,0.00008118892,0.000188628,0.0001214904,0.0003349246,0.0008904321],"category_scores_gemma":[0.0001808049,0.00009906522,0.0001967187,0.00007848668,0.0001792687,0.0001830656,0.0001006421,0.0004788298,0.0001885526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001962362,"about_ca_system_score_gemma":0.0001721484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002687497,"about_ca_topic_score_gemma":0.0002685479,"domain_scores_codex":[0.9998863,0.00002316615,0.000008207158,0.00001948599,0.00003172107,0.00003118371],"domain_scores_gemma":[0.999917,0.00002185226,0.00002243478,0.000007190474,0.00001558512,0.00001587533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001453295,0.0001450061,0.0002413225,0.0000362767,0.000005363336,0.00001878381,0.00001096963,0.000138695,0.9981716,0.00003247614,0.00001987767,0.00103438],"study_design_scores_gemma":[0.00010296,0.009540093,0.007024194,0.00001441628,0.00004953816,0.0002526985,0.00003664938,0.00185489,0.9796817,0.00006408154,0.001372427,0.000006274354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984348,0.0002756579,0.0007586536,0.00003909076,0.00001954216,0.00002259599,0.00006643996,0.00001622414,0.0003668948],"genre_scores_gemma":[0.9978886,0.0002527297,0.0006963727,0.00004142419,0.00001342726,0.00002340837,0.0003086432,0.000003148732,0.0007722027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008904321,"threshold_uncertainty_score":0.002978802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04021052907367511,"score_gpt":0.3270052878613172,"score_spread":0.2867947587876421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}