{"id":"W3174026444","doi":"10.1096/fasebj.2019.33.1_supplement.868.7","title":"Altered Skeletal Muscle Microtubule‐Mitochondrial Voltage Gated‐Dependent Anion Channel (VDAC) 2 Binding is Related to Bioenergetic Impairments after Paclitaxel but not Vinblastine Chemotherapies","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"James H. Cummings Foundation","keywords":"Voltage-dependent anion channel; Vinblastine; Bioenergetics; Mitochondrion; Tubulin; Mitochondrial permeability transition pore; Cell biology; Paclitaxel; Microtubule; Chemistry; Biology; Biochemistry; Biophysics; Programmed cell death; Apoptosis; Bacterial outer membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000722292,0.0002041825,0.0002513564,0.0001865441,0.000131382,0.000199617,0.000114387,0.0003364848,0.00209779],"category_scores_gemma":[0.0001011726,0.0001345563,0.0001552011,0.0001354691,0.000196305,0.000152501,0.0001149219,0.0003758506,0.0002097091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002856519,"about_ca_system_score_gemma":0.0001018808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006989188,"about_ca_topic_score_gemma":0.001087933,"domain_scores_codex":[0.9999034,0.00001154597,0.000009149931,0.00002759341,0.0000162303,0.0000320603],"domain_scores_gemma":[0.9999025,0.00001251615,0.00004612089,0.000005217498,0.000008511765,0.0000251691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005298765,0.00003881622,0.001153557,0.00003034912,0.00001428476,0.00007453699,0.000009373929,0.00002780933,0.9973973,0.00001705185,0.00003366275,0.0006733593],"study_design_scores_gemma":[0.00009338725,0.002237533,0.1718209,0.0000139597,0.00006736304,0.0007024855,0.00008526286,0.0006021868,0.8227246,0.00005272995,0.001593687,0.000005900916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978771,0.0008958066,0.0004660223,0.00005354132,0.00001733931,0.00001961798,0.0001740604,0.00002361049,0.0004729063],"genre_scores_gemma":[0.9971212,0.000530727,0.0002375207,0.0000520828,0.000008838935,0.00004058527,0.0002437695,0.000004078658,0.001761271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00209779,"threshold_uncertainty_score":0.007017791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007844979476166605,"score_gpt":0.2279750411889946,"score_spread":0.220130061712828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}