{"id":"W3174088627","doi":"10.1096/fasebj.2019.33.1_supplement.38.10","title":"<i>Giardia</i> ‐Induced Alterations to Intestinal Mucus Production Involve Protease‐Activated Receptor‐2‐Mediated Activation of MAPK and Calcium Release","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Crohn's and Colitis Canada","keywords":"Mucus; Protease-activated receptor 2; Biology; Proteases; Chinese hamster ovary cell; Cysteine protease; Microbiology; Mucin; Protease; Receptor; Giardia; Molecular biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002190946,0.0007618995,0.0004237005,0.0002437892,0.0001526942,0.0004180856,0.00024833,0.0004706481,0.003996674],"category_scores_gemma":[0.0001354409,0.0002173249,0.0004898784,0.0002067599,0.000383016,0.0002768668,0.0002625573,0.0008362756,0.001098103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004351265,"about_ca_system_score_gemma":0.0001942607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008512172,"about_ca_topic_score_gemma":0.0007401268,"domain_scores_codex":[0.9996651,0.00005866133,0.00002404047,0.00007646415,0.00006922839,0.0001064735],"domain_scores_gemma":[0.9998821,0.00001092199,0.00004803579,0.00001492872,0.00001543939,0.00002852671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000256483,0.00001827856,0.0001378089,0.00009102827,0.000007526559,0.0000707329,0.000008793239,0.00001316689,0.9986733,0.00006101786,0.0001905998,0.0004713483],"study_design_scores_gemma":[0.00005504455,0.0006886306,0.02195266,0.00003119371,0.00003068793,0.0008802551,0.00005425393,0.0006652611,0.9681963,0.00009596617,0.007337611,0.00001197826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9664437,0.009238598,0.008702335,0.001169586,0.000389661,0.0001913832,0.004551649,0.000962611,0.008350637],"genre_scores_gemma":[0.976579,0.002733965,0.005088109,0.000312171,0.0001077682,0.0002202098,0.003807661,0.0001097327,0.01104138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003996674,"threshold_uncertainty_score":0.01337022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01839517954855032,"score_gpt":0.2527323511285474,"score_spread":0.2343371715799971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}