{"id":"W3174150961","doi":"10.1016/j.cell.2021.06.004","title":"Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy","year":2021,"lang":"en","type":"article","venue":"Cell","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; Medical Research Council; Agence Nationale de la Recherche; Cancer Research UK","keywords":"Biology; Genetics; Virology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000173568,0.0003566723,0.0004562061,0.000144345,0.0005765258,0.00004967929,0.0004095678,0.000259329,0.001492001],"category_scores_gemma":[0.00003206832,0.0003188692,0.0001333169,0.0006054642,0.0002165727,0.000100443,0.0001341241,0.0004214731,0.002104481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000589329,"about_ca_system_score_gemma":0.0002006249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002680747,"about_ca_topic_score_gemma":0.0001534771,"domain_scores_codex":[0.9978098,0.0002399993,0.0003971343,0.0006530497,0.00008203363,0.0008180211],"domain_scores_gemma":[0.9987707,0.00007809434,0.0002321607,0.0007115524,0.0001776892,0.00002986473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003933139,0.001954205,0.006532848,0.0002517001,0.00004125924,0.0001260498,0.004081085,0.0002204296,0.9810786,0.00008955818,0.003734558,0.00149639],"study_design_scores_gemma":[0.003959233,0.001035333,0.0291326,0.0001898831,0.00007612063,0.00006109955,0.02565208,0.000002486194,0.6904011,0.00004762013,0.2484211,0.00102129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.944198,0.04414834,0.0001982957,0.0003417658,0.0004897164,0.0003214732,0.00006166286,0.0001538636,0.01008692],"genre_scores_gemma":[0.9803892,0.0002933898,0.00008660689,0.002097406,0.000008227027,0.00004238324,0.00009735024,0.00005668376,0.01692871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2906775,"threshold_uncertainty_score":0.9999263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256122139210199,"score_gpt":0.225075964815533,"score_spread":0.212514743423431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}