{"id":"W3174221329","doi":"10.3390/cells10071642","title":"Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; Rebecca L. Cooper Medical Research Foundation","keywords":"Unfolded protein response; XBP1; Idiopathic pulmonary fibrosis; Autophagy; Lung; Pulmonary fibrosis; DLCO; Apoptosis; Medicine; Cancer research; Biology; Pathology; Immunology; Internal medicine; Diffusing capacity; Lung function; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004650166,0.0001900262,0.0002888465,0.00009305433,0.0001395604,0.00005194002,0.00008180454,0.0001447719,0.0001415617],"category_scores_gemma":[0.00009620257,0.0001467562,0.0001320273,0.0003544365,0.0001066033,0.0001160267,0.0001028004,0.000306538,0.00002781787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001058536,"about_ca_system_score_gemma":0.0002493959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005042472,"about_ca_topic_score_gemma":0.000003604795,"domain_scores_codex":[0.9984413,0.0002901265,0.0003178671,0.0003960361,0.0002511522,0.000303552],"domain_scores_gemma":[0.9992272,0.00007512381,0.00006773596,0.0003938774,0.00009273808,0.0001433491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009426291,0.0002457704,0.0007822198,0.0004880215,0.0000399663,0.0003125254,0.0001815371,0.000006805681,0.9847524,0.0002843364,0.0008989269,0.002581243],"study_design_scores_gemma":[0.003484158,0.00373814,0.1771696,0.005252756,0.0007941595,0.0005309694,0.001889221,0.006615206,0.7806133,0.001495937,0.01745321,0.0009633931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869609,0.008360612,0.00006945323,0.002369268,0.0003169719,0.0006125063,0.00002766489,0.00005888342,0.001223725],"genre_scores_gemma":[0.9961264,0.0001743155,0.0000850033,0.0005550057,0.0002026359,0.000091226,0.000027754,0.00002865705,0.002709029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2041391,"threshold_uncertainty_score":0.5984542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006853907414019349,"score_gpt":0.2267534196674859,"score_spread":0.2198995122534666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}