{"id":"W3174221329","doi":"10.3390/cells10071642","title":"Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; Rebecca L. Cooper Medical Research Foundation","keywords":"Unfolded protein response; XBP1; Idiopathic pulmonary fibrosis; Autophagy; Lung; Pulmonary fibrosis; DLCO; Apoptosis; Medicine; Cancer research; Biology; Pathology; Immunology; Internal medicine; Diffusing capacity; Lung function; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007474672,0.0002031386,0.0003010144,0.000947773,0.0002362741,0.0002677089,0.0001741658,0.000361384,0.0003523763],"category_scores_gemma":[0.0006776513,0.0001094807,0.000220603,0.0006033421,0.0004209705,0.0002971426,0.0003056865,0.0004030393,0.00004702077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002720449,"about_ca_system_score_gemma":0.0002603408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009406749,"about_ca_topic_score_gemma":0.001325992,"domain_scores_codex":[0.9996963,0.0001270597,0.00003732329,0.00004997401,0.0000548822,0.00003454814],"domain_scores_gemma":[0.9995567,0.0001272545,0.000180246,0.00001817663,0.00004156976,0.00007594383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002897327,0.0005504911,0.9412447,0.0002733876,0.0001125269,0.001596111,0.000260472,0.0004198056,0.02170657,0.0002745827,0.000232292,0.03043183],"study_design_scores_gemma":[0.0000142945,0.0004710965,0.9959745,0.00002443688,0.00004763966,0.001345381,0.0001326282,0.0005360295,0.0009381111,0.0002568662,0.0002534071,0.000005607265],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9883204,0.01081716,0.0003495342,0.0001445327,0.000007684249,0.00001266171,0.00004528991,0.000004979987,0.000297798],"genre_scores_gemma":[0.9975854,0.001813287,0.0003218802,0.00004933721,0.00002790055,0.00001437292,0.00005148805,8.720482e-7,0.000135337],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.000947773,"threshold_uncertainty_score":0.00395304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006853907414019349,"score_gpt":0.2267534196674859,"score_spread":0.2198995122534666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}