{"id":"W3174255972","doi":"10.1096/fasebj.2019.33.1_supplement.774.20","title":"<i>EFTUD2</i> , The Gene Responsible For Mandibulofacial Dysostosis With Microcephaly (MFDM), Is Required For Implantation And Craniofacial Development In Mouse","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Craniofacial Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill Genome Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Craniofacial; Microcephaly; Haploinsufficiency; Embryo; Exon; Transgene; Genetics; In situ hybridization; Neural crest; Molecular biology; Gene; Phenotype; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008959095,0.0006449469,0.0002373036,0.0005189105,0.0002637184,0.0002841482,0.0003208735,0.0004815698,0.003769065],"category_scores_gemma":[0.00009375448,0.0002825799,0.0003276262,0.0002011717,0.0003608261,0.0001491018,0.0003400738,0.0006222009,0.001448963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002922595,"about_ca_system_score_gemma":0.0001425725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000611003,"about_ca_topic_score_gemma":0.001220461,"domain_scores_codex":[0.9998475,0.00001318002,0.0000160316,0.00005177828,0.0000436901,0.00002762377],"domain_scores_gemma":[0.9998816,0.00001583028,0.00005564732,0.00001027028,0.000006042289,0.00003047591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004732212,0.000008386022,0.0002093153,0.00002321166,0.00000349061,0.0003150065,0.000008018208,0.00003128201,0.9979704,0.0001256025,0.0001068748,0.001151108],"study_design_scores_gemma":[0.00003397362,0.0001190865,0.01714985,0.00002241544,0.00002355217,0.004490286,0.00003954499,0.0009604435,0.9610181,0.0001011003,0.01602698,0.00001445172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746646,0.001710563,0.009628896,0.0003012023,0.0001023077,0.00005559002,0.004916165,0.0009138534,0.007706875],"genre_scores_gemma":[0.969959,0.0007221391,0.007603756,0.000221859,0.00002731918,0.0000892958,0.005775174,0.0002978219,0.0153036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003769065,"threshold_uncertainty_score":0.01260877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00969444033070026,"score_gpt":0.2399893663196691,"score_spread":0.2302949259889688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}