{"id":"W3174287136","doi":"10.1096/fasebj.23.1_supplement.1001.6","title":"Renal Collecting Duct GSK3ß Deletion Affects Response To AVP By Reducing Adenylate Cyclase Activity","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Internal medicine; Endocrinology; Aquaporin 2; Reabsorption; Forskolin; Urine osmolality; GSK-3; Adenylate kinase; Vasopressin; Chemistry; Kidney; Biology; Kinase; Medicine; Biochemistry; Stimulation; Receptor; Water channel","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472059,0.000589252,0.000278449,0.000414008,0.0001770398,0.0004007843,0.0002582803,0.000487439,0.003970529],"category_scores_gemma":[0.0001493308,0.0003082229,0.0004737337,0.0002506014,0.0004947152,0.0002749814,0.00021032,0.0008284383,0.0007076417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003196342,"about_ca_system_score_gemma":0.0002959272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007451543,"about_ca_topic_score_gemma":0.001135678,"domain_scores_codex":[0.9997951,0.00002569062,0.00003258725,0.00005700567,0.0000395011,0.00005014242],"domain_scores_gemma":[0.9997398,0.00003039149,0.0001134689,0.00002318846,0.00001371081,0.0000793875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002847287,0.00002855198,0.0002768162,0.00004536751,0.000007249372,0.00009850456,0.00001124067,0.0000452932,0.9983791,0.00009264261,0.00005708232,0.000673388],"study_design_scores_gemma":[0.0001198934,0.0003037475,0.01078197,0.00001349616,0.00004915676,0.0006568978,0.00005832686,0.000626778,0.984318,0.000111549,0.002949857,0.00001035469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923635,0.001671656,0.002224754,0.0002510814,0.00008016019,0.000033166,0.001322136,0.0002201492,0.001833434],"genre_scores_gemma":[0.9929113,0.0009100948,0.001654365,0.00008559412,0.00001561814,0.00006147981,0.0006637553,0.0000715951,0.003626185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003970529,"threshold_uncertainty_score":0.01328278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009798231745652926,"score_gpt":0.2482124883706156,"score_spread":0.2384142566249627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}