{"id":"W3174311122","doi":"10.1096/fasebj.21.6.a796","title":"Integrating cAMP and phospholipid signaling: role of phosphodiesterase 3B","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Second messenger system; Phosphodiesterase; Adenylyl cyclase; Cell biology; Phosphodiesterase 3; Effector; PDE10A; Extracellular; Subcellular localization; Intracellular; Cyclic adenosine monophosphate; Signal transduction; Biology; Context (archaeology); Cell signaling; Cyclic nucleotide phosphodiesterase; Biochemistry; Enzyme; Receptor; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000748081,0.0001128757,0.0001111034,0.00003567455,0.0002017722,0.0000348959,0.0001084673,0.00007298643,0.00003612956],"category_scores_gemma":[0.00007426896,0.00007284787,0.00007306481,0.00006610192,0.0001172103,0.00000708282,0.0000511193,0.0001619132,0.000002105012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001251375,"about_ca_system_score_gemma":0.0000413128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001531069,"about_ca_topic_score_gemma":0.00001983021,"domain_scores_codex":[0.9992396,0.00004655381,0.0002802593,0.0001205432,0.0001331854,0.0001799082],"domain_scores_gemma":[0.9994208,0.00003421501,0.0001953123,0.0001484091,0.0001099634,0.00009134367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002069794,0.00002350804,0.005580981,0.000004250725,0.00003897944,0.000002639951,0.0004753383,0.00004629406,0.9832836,0.000105632,0.0001806958,0.01005108],"study_design_scores_gemma":[0.0004359244,0.0001581723,0.002865411,0.00002756206,0.00002141064,0.0002566804,0.001604287,0.00007753009,0.9897226,0.0002305962,0.004504033,0.00009580307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924341,0.002271663,0.004203475,0.00007357597,0.0002519752,0.00006939731,0.000003910729,0.000005212101,0.0006866521],"genre_scores_gemma":[0.9983762,0.000152114,0.0006397367,0.0002072059,0.0003015066,0.000001071652,0.00001011267,0.0000116599,0.0003004064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009955272,"threshold_uncertainty_score":0.297065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007344551428038163,"score_gpt":0.2318404107194551,"score_spread":0.2244958592914169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}