{"id":"W3174463899","doi":"10.1101/2021.06.18.448919","title":"After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Astrocyte; Glial fibrillary acidic protein; Oligodendrocyte; Glial scar; Transgene; Biology; Genetically modified mouse; Microglia; Cell biology; Lesion; Neuroglia; Pathology; Molecular biology; Neuroscience; Immunology; Medicine; Immunohistochemistry; Gene; Myelin; Central nervous system; Genetics; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006679826,0.0003218815,0.0001579945,0.0001829122,0.0001743231,0.0002748448,0.00009622822,0.0002241561,0.0009390402],"category_scores_gemma":[0.00007832621,0.00009879796,0.0001810607,0.0001386056,0.0002409544,0.0001564359,0.0002281899,0.0003724617,0.0003818199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001031629,"about_ca_system_score_gemma":0.0001453437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003636896,"about_ca_topic_score_gemma":0.0005619065,"domain_scores_codex":[0.9999158,0.000006732218,0.000006743122,0.00001229321,0.00003050568,0.00002784722],"domain_scores_gemma":[0.9999205,0.000005691316,0.00002931742,0.0000100983,0.00001181867,0.00002263447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004459963,0.000007929121,0.0003346016,0.00003403348,0.000003624436,0.0002066706,0.00003171486,0.00002580953,0.9982175,0.00005501336,0.00001731445,0.001021165],"study_design_scores_gemma":[0.000007335803,0.0004487534,0.02118921,0.00002196458,0.00002177346,0.001849684,0.000207198,0.0003350041,0.9722558,0.000238408,0.003416216,0.000008692586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930031,0.001311999,0.003815761,0.00004162888,0.00002351819,0.00003021575,0.0001884284,0.00009818235,0.001487177],"genre_scores_gemma":[0.9932734,0.001410649,0.001208125,0.00004778219,0.00001154936,0.00004441955,0.0003016088,0.00001986478,0.003682547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009390402,"threshold_uncertainty_score":0.003141403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02140037717126849,"score_gpt":0.2323579314044176,"score_spread":0.2109575542331491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}