{"id":"W3174703840","doi":"10.1096/fasebj.20.4.a817","title":"Effect of thyroid hormone on oxidative stress in cells from patients with mtDNA defects","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Mitochondrial biogenesis; TFAM; Mitochondrial DNA; Oxidative stress; Mitochondrion; Biology; Mitochondrial disease; Reactive oxygen species; Oxidative phosphorylation; Mitochondrial ROS; Molecular biology; Internal medicine; Cell biology; Endocrinology; Chemistry; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002316913,0.0003125524,0.000449176,0.0002547335,0.0002764801,0.0002674326,0.0001726051,0.0003559237,0.001602401],"category_scores_gemma":[0.0004811665,0.0001396307,0.0004219211,0.000201593,0.0002389061,0.0001153116,0.000217487,0.0005342934,0.0003093607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002216384,"about_ca_system_score_gemma":0.0003079241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002131962,"about_ca_topic_score_gemma":0.002587545,"domain_scores_codex":[0.9998166,0.00006050432,0.00002335517,0.00002891414,0.00003915166,0.00003161365],"domain_scores_gemma":[0.9997829,0.00007119719,0.00002593393,0.00002483648,0.00002891377,0.00006613449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006224727,0.0004142013,0.00390932,0.00009013664,0.00006391779,0.001291305,0.000258098,0.00009276935,0.9815102,0.00003693116,0.0002760981,0.005832419],"study_design_scores_gemma":[0.001707024,0.03603195,0.1344092,0.00005527034,0.0004233852,0.00735148,0.0009015459,0.001931248,0.8072494,0.0001658986,0.00972084,0.00005260139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997824,0.001430609,0.000116534,0.00009317555,0.00004199146,0.00001696312,0.0001190853,0.00001585142,0.0003418591],"genre_scores_gemma":[0.9975895,0.000796532,0.0003346746,0.00009606365,0.00002268453,0.00002270648,0.0004744972,0.000006975538,0.0006564732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002131962,"threshold_uncertainty_score":0.005360603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003511346317923097,"score_gpt":0.2002325477877848,"score_spread":0.1967212014698617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}