{"id":"W3174722268","doi":"10.1096/fasebj.2018.32.1_supplement.103.1","title":"Probing the structure, dynamics and regulation of lipid signalling enzymes and their role in human disease","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Kinase; Biology; Cell biology; Phosphoinositide 3-kinase; Signal transduction; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005567887,0.0002643026,0.0002254088,0.0003701003,0.0001696985,0.0005254474,0.0003196174,0.0009040027,0.0009965175],"category_scores_gemma":[0.0004664226,0.0001834073,0.0002253177,0.000307373,0.0005603865,0.000748684,0.0003239027,0.000992173,0.0003281251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005993858,"about_ca_system_score_gemma":0.0002874648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007762778,"about_ca_topic_score_gemma":0.0005877953,"domain_scores_codex":[0.999869,0.00003664307,0.00000703775,0.00003628053,0.00002757977,0.00002353163],"domain_scores_gemma":[0.9998721,0.00003771727,0.00003775181,0.00001262734,0.00001542776,0.00002435646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007468004,0.0001628515,0.02102989,0.0007566703,0.0001131108,0.0008505119,0.0005330034,0.002849549,0.846018,0.01954148,0.007585369,0.09981269],"study_design_scores_gemma":[0.00009397296,0.001222341,0.09344254,0.0004149707,0.0001887552,0.007545055,0.001330905,0.009753399,0.590222,0.04162141,0.2540647,0.0000998364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6689224,0.2465602,0.03317859,0.03286435,0.000635231,0.00006072505,0.001498622,0.0002584274,0.01602144],"genre_scores_gemma":[0.8706172,0.1103191,0.01228365,0.002221996,0.0002668813,0.00004646143,0.0005408906,0.00002846551,0.003675411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009965175,"threshold_uncertainty_score":0.004348874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852968757226979,"score_gpt":0.2885559685593704,"score_spread":0.2700262809871006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}