{"id":"W3174868402","doi":"10.1096/fasebj.2019.33.1_supplement.537.7","title":"The Effect of Chronic Contractile Activity and Retinoic Acid on Mitochondrial Turnover in C2C12 Myotubes","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Myogenesis; Mitochondrial biogenesis; Retinoic acid; Mitochondrion; C2C12; Autophagy; Cell biology; Myocyte; Retinoic acid receptor; Mitochondrial DNA; Protein subunit; Mitochondrial myopathy; Mitophagy; Biology; Chemistry; Biochemistry; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002878318,0.0002937927,0.0005555596,0.0002327962,0.0002719896,0.0003351239,0.000254074,0.0003863137,0.001336442],"category_scores_gemma":[0.0001422793,0.0001871855,0.0005756999,0.0003033211,0.0002416174,0.0002594683,0.0002205958,0.0008252921,0.0003832702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003439647,"about_ca_system_score_gemma":0.0004377736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003614857,"about_ca_topic_score_gemma":0.0080863,"domain_scores_codex":[0.99968,0.00004890979,0.0000624653,0.00007349655,0.00006378072,0.00007139472],"domain_scores_gemma":[0.9997798,0.00004399183,0.0000389926,0.00003520175,0.00004845465,0.00005363052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001634561,0.0001815826,0.0006110623,0.0001674311,0.00002390142,0.00008923311,0.00007149747,0.00007264016,0.9947519,0.00004759462,0.0001202339,0.002228349],"study_design_scores_gemma":[0.0001391556,0.003580246,0.0268974,0.00004042727,0.00009997081,0.0002005277,0.0002389015,0.000682799,0.9639357,0.00003442667,0.004135343,0.00001515508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903173,0.005805555,0.0006179303,0.0001756132,0.00008139363,0.00003729881,0.001029531,0.00003741225,0.001897994],"genre_scores_gemma":[0.9855766,0.003986489,0.002028889,0.0001350084,0.00003606359,0.0001456004,0.001625259,0.00002371486,0.006442269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003614857,"threshold_uncertainty_score":0.007187605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004673345877146513,"score_gpt":0.229290430658727,"score_spread":0.2246170847815805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}