{"id":"W3174912361","doi":"10.3389/fimmu.2021.714808","title":"Underwhelming or Misunderstood? Genetic Variability of Pattern Recognition Receptors in Immune Responses and Resistance to Mycobacterium tuberculosis","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; McGill University Health Centre; McGill University","keywords":"Immune system; Mycobacterium tuberculosis; Immune recognition; Pattern recognition receptor; Immunology; Tuberculosis; Biology; Medicine; Computational biology; Innate immune system; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002136871,0.0003729456,0.001021693,0.0009315344,0.000509756,0.002302115,0.0008256091,0.001456569,0.002152426],"category_scores_gemma":[0.005718539,0.0001856175,0.0002896277,0.001159659,0.003295693,0.004055647,0.001237046,0.00230098,0.0007925798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005583817,"about_ca_system_score_gemma":0.001319913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009513792,"about_ca_topic_score_gemma":0.000862291,"domain_scores_codex":[0.999069,0.0004134767,0.0001089497,0.0001735912,0.0001633451,0.00007150523],"domain_scores_gemma":[0.9971173,0.001899407,0.0003506537,0.0001113691,0.0003503578,0.0001708606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004070661,0.00008982403,0.004866571,0.01508496,0.0002859025,0.001736139,0.00990918,0.0004335183,0.004423249,0.06261989,0.2091025,0.6910411],"study_design_scores_gemma":[0.00001954937,0.0001430164,0.00536117,0.006726786,0.0001031823,0.002541693,0.004467469,0.0001322694,0.0007094421,0.05585291,0.9238908,0.00005164341],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003699701,0.9520954,0.0006375259,0.03063036,0.009970077,0.000005457085,0.00005790516,0.00001690775,0.002886699],"genre_scores_gemma":[0.03043434,0.9254181,0.000559682,0.02240862,0.01666898,0.00001596799,0.00008792216,0.00003019841,0.004376243],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002302115,"threshold_uncertainty_score":0.01130098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05006688053354909,"score_gpt":0.3359758928718592,"score_spread":0.2859090123383101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}