{"id":"W3174930272","doi":"10.1096/fasebj.22.1_supplement.1238.12","title":"Decreased anti‐apoptotic ARC and XIAP as well as elevated pro‐apoptotic Smac and procaspase‐8 protein in soleus muscle of hypertensive rats","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"XIAP; Apoptosis; Skeletal muscle; Endocrinology; Internal medicine; Soleus muscle; Western blot; Inhibitor of apoptosis; Caspase; Caspase 12; Chemistry; Myocyte; Medicine; Biochemistry; Gene; Programmed cell death","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001723671,0.0006006271,0.0005783599,0.0007049063,0.0001868663,0.0002123852,0.0001734452,0.0002800681,0.001811876],"category_scores_gemma":[0.0001222412,0.0003089702,0.0003724777,0.0002016049,0.0002626111,0.0002953916,0.0002306234,0.0008190763,0.0002620429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002305179,"about_ca_system_score_gemma":0.0002220233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001445831,"about_ca_topic_score_gemma":0.001903552,"domain_scores_codex":[0.9997973,0.00001835456,0.00002710166,0.00004907505,0.00005499841,0.00005329521],"domain_scores_gemma":[0.9996738,0.00001432631,0.00009638711,0.00002279138,0.0000422411,0.0001504076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003346417,0.00002985733,0.0004488627,0.00003223456,0.00001056423,0.00004412796,0.00001735993,0.000008135791,0.9983428,0.0000111872,0.00001283871,0.0007074426],"study_design_scores_gemma":[0.0001062291,0.002398442,0.1963853,0.00001875893,0.0001405733,0.0008377144,0.0002245193,0.0008826153,0.7978163,0.00007740446,0.001093214,0.00001905265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979971,0.0006196657,0.000841181,0.00005903053,0.00001945511,0.00000876963,0.0001798747,0.00003984273,0.0002350814],"genre_scores_gemma":[0.9920729,0.001186503,0.001885873,0.00007907471,0.00002693116,0.00005884993,0.0005711015,0.00002915212,0.00408969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001811876,"threshold_uncertainty_score":0.006061256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840681552503689,"score_gpt":0.2517274842251252,"score_spread":0.2333206687000883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}