{"id":"W3174972732","doi":"10.3390/foods10071476","title":"Impact of Hydrolyzed Collagen from Defatted Sea Bass Skin on Proliferation and Differentiation of Preosteoblast MC3T3-E1 Cells","year":2021,"lang":"en","type":"article","venue":"Foods","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Prince of Songkla University; National Science and Technology Development Agency","keywords":"RUNX2; Chemistry; Alkaline phosphatase; Cell growth; Protein kinase B; Osteoblast; Western blot; Internal medicine; Endocrinology; Apoptosis; Biochemistry; Biology; Enzyme; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006258778,0.0001227347,0.0001953925,0.00003224672,0.00003001375,0.00001519668,0.0000595783,0.0001224749,0.00004079154],"category_scores_gemma":[0.00004438157,0.0001032468,0.0001154735,0.00008587915,0.00003787633,0.000004758093,0.0000593841,0.00003272151,0.000001053171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001335308,"about_ca_system_score_gemma":0.0000633614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007326675,"about_ca_topic_score_gemma":0.00007908369,"domain_scores_codex":[0.9991951,0.0001090644,0.0002086732,0.0002558746,0.0001236571,0.0001076427],"domain_scores_gemma":[0.9994648,0.00001932615,0.0001576364,0.0001944674,0.0001202407,0.00004356658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002437299,0.0001559345,0.02417231,0.00001950476,0.0001946731,5.142343e-7,0.00004467314,0.0001059634,0.9740331,0.000003687609,0.00007772805,0.000948176],"study_design_scores_gemma":[0.0005932541,0.000681379,0.1279784,0.00002261282,0.00003796154,7.581912e-7,0.00001156719,0.00070326,0.869811,0.00003318622,0.00003719315,0.0000895025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998576,0.0002188178,0.0005211348,0.00002480523,0.00002646437,0.0001993135,0.0002655908,0.000003813608,0.0001640308],"genre_scores_gemma":[0.9990187,0.00006055975,0.0003026917,0.00001778177,0.00007362226,0.00001408281,0.0004372163,0.00001137326,0.0000639417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1042221,"threshold_uncertainty_score":0.4210283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007507376216432348,"score_gpt":0.2434899902209709,"score_spread":0.2359826140045385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}