{"id":"W3174988055","doi":"10.1096/fasebj.23.1_supplement.360.8","title":"Talin mediates monocyte α4β1 integrin‐mediated migration, but not chemokine‐triggered α4β1 affinity up‐regulation or adhesion","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Integrin; Cell biology; Chemotaxis; Integrin, beta 6; Chemistry; Integrin alpha M; Focal adhesion; Cell adhesion; Chemokine; Molecular biology; Adhesion; Receptor; Biology; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000167966,0.0004626208,0.0002842791,0.0002260562,0.0003033818,0.0003626044,0.0003041038,0.0003612324,0.002547508],"category_scores_gemma":[0.00012696,0.0001648901,0.0003490023,0.0001847513,0.0001972845,0.0002540929,0.0002477109,0.0006290762,0.000885186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005201217,"about_ca_system_score_gemma":0.000314993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008605451,"about_ca_topic_score_gemma":0.001156517,"domain_scores_codex":[0.9997731,0.00002985207,0.00001714983,0.00003388727,0.00005725777,0.00008875837],"domain_scores_gemma":[0.999915,0.0000159299,0.0000181126,0.000008597649,0.00001006231,0.00003229986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007826951,0.00002287575,0.00004707279,0.00004441873,0.000003505889,0.000038046,0.00001542717,0.00003217684,0.99897,0.0001206077,0.00008915544,0.0005385929],"study_design_scores_gemma":[0.00001543175,0.00009747867,0.002592916,0.000006022782,0.00001237763,0.0001273173,0.00002210058,0.0009117294,0.9934556,0.00003371299,0.002722445,0.000002875506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909389,0.001488231,0.003949943,0.0002084265,0.0000535502,0.00003996773,0.0005614475,0.0001028147,0.002656793],"genre_scores_gemma":[0.9884045,0.001054038,0.001426497,0.00009921308,0.00001972596,0.00006969012,0.001245987,0.0000239973,0.007656368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002547508,"threshold_uncertainty_score":0.008522272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04276237926807703,"score_gpt":0.3087992369694236,"score_spread":0.2660368577013466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}