{"id":"W3175005768","doi":"10.1096/fasebj.27.1_supplement.695.2","title":"MR or AT1R gene silencing in the PVN markedly attenuates Ang II‐induced hypertension in rats","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Gene silencing; Angiotensin II; Small interfering RNA; Endogeny; Chemistry; Endocrinology; Molecular biology; Medicine; Messenger RNA; Internal medicine; Gene; Biology; Receptor; RNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002493093,0.000710256,0.0008416461,0.0004062732,0.0001997565,0.0003557939,0.00033863,0.0003781237,0.001750711],"category_scores_gemma":[0.0001964743,0.0003226711,0.0003985334,0.0001526315,0.0005974276,0.0004461839,0.0002232875,0.0015022,0.0005191331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002961205,"about_ca_system_score_gemma":0.0004821672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001081131,"about_ca_topic_score_gemma":0.001632663,"domain_scores_codex":[0.9996953,0.00004198777,0.0000290399,0.00008204357,0.00005976213,0.00009195905],"domain_scores_gemma":[0.9996576,0.00002569032,0.0001168347,0.00003386533,0.00003105993,0.0001348787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007723506,0.0001649069,0.0001312514,0.00004605525,0.00000960029,0.00003375444,0.0000300872,0.00006048926,0.996615,0.00007437086,0.00006921517,0.001992891],"study_design_scores_gemma":[0.000143825,0.004179553,0.006207983,0.00001884357,0.0000641134,0.0002042023,0.00008629006,0.001629565,0.9853865,0.0001101275,0.001953475,0.00001558076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921603,0.0009141649,0.004673475,0.0002262516,0.0001072433,0.0000426927,0.0003721067,0.0003467096,0.001157051],"genre_scores_gemma":[0.9798166,0.00159688,0.008142811,0.0002158148,0.00008098961,0.000228224,0.0007071825,0.0001498651,0.009061662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001750711,"threshold_uncertainty_score":0.005856693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05935766932240968,"score_gpt":0.2913706640914304,"score_spread":0.2320129947690207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}