{"id":"W3175061289","doi":"10.1016/j.jad.2021.06.032","title":"Efficacy of ketamine and esketamine on functional outcomes in treatment-resistant depression: A systematic review","year":2021,"lang":"en","type":"review","venue":"Journal of Affective Disorders","topic":"Treatment of Major Depression","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Ketamine; Treatment-resistant depression; Psychosocial; Medicine; Depression (economics); Rating scale; Psychology; Clinical psychology; Meta-analysis; Major depressive disorder; Internal medicine; Psychiatry; Mood; Developmental psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003189349,0.00119812,0.008987241,0.002544333,0.0003973449,0.001829439,0.00162617,0.001762526,0.003742767],"category_scores_gemma":[0.01324654,0.0007781842,0.009162582,0.003549341,0.000665357,0.001397682,0.001098352,0.001540784,0.0002178389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001756332,"about_ca_system_score_gemma":0.003747549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007550417,"about_ca_topic_score_gemma":0.02658698,"domain_scores_codex":[0.9980915,0.0005710123,0.0006998558,0.0002289791,0.0003162241,0.0000923316],"domain_scores_gemma":[0.9938023,0.004374202,0.001288479,0.00008411829,0.000324405,0.0001264855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.001602593,0.00005540782,0.001183117,0.9023588,0.05088152,0.0000911598,0.0001169959,0.0001566944,0.0002285971,0.0001379441,0.001241191,0.04194595],"study_design_scores_gemma":[0.003176465,0.0009271582,0.01265869,0.3938976,0.5754508,0.0003882309,0.0003281462,0.0002324442,0.0003041828,0.0004061008,0.01213885,0.0000913593],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001600961,0.9978657,0.00006977846,0.00007012075,0.00006741947,0.00009049739,0.0001276881,0.000005688006,0.0001021577],"genre_scores_gemma":[0.02486234,0.9740579,0.0003497345,0.000332587,0.0000568565,0.0001228274,0.0001257103,0.000003793227,0.000088173],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008987241,"threshold_uncertainty_score":0.0168671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0283587224555213,"score_gpt":0.3447387972673632,"score_spread":0.3163800748118419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}