{"id":"W3175153285","doi":"10.1101/2021.06.30.450517","title":"Identification of transcription termination defects at DNA hypomethylated transcription termination sites in DNA methyltransferase 3a-deficient vertebrates","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science","keywords":"DNA methylation; Biology; Epigenetics of physical exercise; RNA-Directed DNA Methylation; Transcription (linguistics); Epigenetics; Methyltransferase; Methylation; Zebrafish; Epigenomics; Gene; DNA methyltransferase; Promoter; Molecular biology; Genetics; Cell biology; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002489857,0.0003741475,0.0004457571,0.0006216822,0.0002075573,0.0003404192,0.0003021931,0.0003964665,0.001553055],"category_scores_gemma":[0.0002657649,0.0002339256,0.0004994012,0.0003960876,0.0002364465,0.0001594662,0.0003587486,0.0005631215,0.000829008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003441815,"about_ca_system_score_gemma":0.000201688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001210423,"about_ca_topic_score_gemma":0.001788176,"domain_scores_codex":[0.9997291,0.00001803413,0.00002640752,0.0001046759,0.00009004844,0.00003157503],"domain_scores_gemma":[0.9996982,0.00005582111,0.0001246976,0.00005024784,0.00002461753,0.00004645885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005215884,0.000003103604,0.0008174332,0.00002731407,0.00001025414,0.00003901498,0.000009808323,0.00007971885,0.9981638,0.00003123834,0.00003935985,0.0007268896],"study_design_scores_gemma":[0.00001307182,0.00008088049,0.06036852,0.00001881147,0.00005817287,0.0004950964,0.00003452794,0.003548563,0.9318296,0.0001782684,0.003362383,0.00001199984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658285,0.0008995936,0.01915091,0.00009200139,0.00003697746,0.00002786354,0.01234607,0.0008980322,0.0007200061],"genre_scores_gemma":[0.9429512,0.0007044551,0.02993047,0.0001183285,0.0000156584,0.00007550553,0.02255385,0.0005530004,0.003097487],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001553055,"threshold_uncertainty_score":0.005195498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211739394385761,"score_gpt":0.2304637910285384,"score_spread":0.2183463970846808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}