{"id":"W3175186896","doi":"10.3390/cells10071568","title":"Senescence and Aging: Does It Impact Cancer Immunotherapies?","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Cancer Research Society","keywords":"Senescence; Immune system; Cancer; Cellular senescence; Immunology; Immunosenescence; Biology; Immune checkpoint; Cancer cell; Cancer research; Immunotherapy; Medicine; Cell biology; Genetics; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007674544,0.0006382655,0.001352829,0.001417795,0.0003060265,0.001155395,0.0007679895,0.001467036,0.003263574],"category_scores_gemma":[0.001168953,0.0001984936,0.0005014572,0.001102697,0.0005204044,0.001565506,0.0006557148,0.002147835,0.001736413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000535388,"about_ca_system_score_gemma":0.0009073094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007805739,"about_ca_topic_score_gemma":0.00149109,"domain_scores_codex":[0.9997571,0.00005784847,0.00003664459,0.00003673276,0.00008812682,0.00002368479],"domain_scores_gemma":[0.9994699,0.0002945299,0.00005242791,0.00001531527,0.0001291286,0.00003870358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008121145,0.00006200352,0.0001511952,0.01558967,0.00008503017,0.0001279284,0.0000911205,0.0002442682,0.001250975,0.005778417,0.03663508,0.9399032],"study_design_scores_gemma":[0.00001349887,0.00012936,0.0006307116,0.005260041,0.00009689738,0.000869862,0.0000718575,0.00006748766,0.0002962956,0.002767857,0.989781,0.00001510898],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005176604,0.9987926,0.00004756094,0.0004504704,0.0002609431,0.000001722969,0.000007311472,0.000003461939,0.0003842374],"genre_scores_gemma":[0.0004681553,0.9984496,0.00006862307,0.0003418444,0.0003223941,0.000003537768,0.00001240558,0.000001147836,0.0003322244],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003263574,"threshold_uncertainty_score":0.01091772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04263669213797455,"score_gpt":0.3832430714180427,"score_spread":0.3406063792800682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}