{"id":"W3175200995","doi":"10.3389/fonc.2021.615296","title":"M6A “Writer” Gene METTL14: A Favorable Prognostic Biomarker and Correlated With Immune Infiltrates in Rectal Cancer","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Fundamental Research Funds for Central Universities of the Central South University; Fundamental Research Funds for the Central Universities; Central South University; National Natural Science Foundation of China","keywords":"Colorectal cancer; Immune system; Immunotherapy; Infiltration (HVAC); Medicine; Cancer research; Oncology; Gene; Cancer; Internal medicine; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002413373,0.0002486586,0.0002997849,0.0005651696,0.0002564511,0.0004154017,0.0001547678,0.0004004998,0.001208059],"category_scores_gemma":[0.0006972203,0.0001412065,0.0002455864,0.0005341394,0.0002411438,0.0001702652,0.0002542519,0.0003854285,0.0002132972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001744407,"about_ca_system_score_gemma":0.0001579665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004905585,"about_ca_topic_score_gemma":0.0007513608,"domain_scores_codex":[0.9998554,0.00003453404,0.00001341168,0.00003746526,0.00002945582,0.00002966534],"domain_scores_gemma":[0.9996144,0.00006306797,0.0001773592,0.00002331795,0.00005026376,0.00007166807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002190776,0.00006791447,0.8798734,0.0001121488,0.0001275368,0.0008176564,0.00009537917,0.0003742701,0.1023774,0.0001144255,0.0003679736,0.01348125],"study_design_scores_gemma":[0.00003004257,0.000427131,0.9732233,0.00002028966,0.0001719479,0.002430485,0.0001649624,0.002751049,0.01842776,0.0003072998,0.002023384,0.00002240557],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976851,0.0009570799,0.0006758214,0.0000879998,0.00001677526,0.00001024421,0.0001884646,0.00001846369,0.000360119],"genre_scores_gemma":[0.998396,0.000201057,0.0007074317,0.00003373555,0.0000150928,0.000008111835,0.0002130065,0.000004835804,0.0004206616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001208059,"threshold_uncertainty_score":0.004041374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009820854612132907,"score_gpt":0.2644930136307933,"score_spread":0.2546721590186604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}