{"id":"W3175268542","doi":"10.1161/atvb.36.suppl_1.444","title":"Abstract 444: Semaphorin3A Reduces Atherosclerotic Plaque Formation in ApoE Knock Out Mice Through Regulation of M2 Type Macrophage Migration","year":2016,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Macrophage; CD68; Inflammation; Fibrous cap; Immune system; Brachiocephalic artery; Apolipoprotein E; Semaphorin; Integrin alpha M; Receptor; Cell biology; Chemistry; Biology; Immunology; Pathology; Medicine; Aorta; Immunohistochemistry; Internal medicine; In vitro; Aortic arch; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635469,0.0009489132,0.0006675711,0.0007907076,0.0003218201,0.0004356175,0.0003095409,0.0008617218,0.004467226],"category_scores_gemma":[0.0001650997,0.0003230633,0.0005534719,0.0001830867,0.0004282352,0.0002537429,0.000231189,0.001229469,0.001192708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003655729,"about_ca_system_score_gemma":0.0003887546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000753079,"about_ca_topic_score_gemma":0.0007959002,"domain_scores_codex":[0.9997229,0.00005082734,0.00003277632,0.00004246938,0.00008088184,0.00007005069],"domain_scores_gemma":[0.9997248,0.00002373653,0.00009250483,0.00002017292,0.0000333755,0.0001053992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007942292,0.0002077882,0.0001320077,0.00005613886,0.00001516098,0.00004539527,0.00001196398,0.00003813427,0.9973289,0.00005639089,0.0001526255,0.001161249],"study_design_scores_gemma":[0.000383518,0.002471039,0.007499247,0.00003521174,0.0000843184,0.0002718015,0.00004169512,0.0007329943,0.9854596,0.0001318446,0.002875982,0.00001258875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922002,0.001264142,0.00202836,0.0004056785,0.00009810802,0.00007776401,0.001096474,0.0005154851,0.002313934],"genre_scores_gemma":[0.9692872,0.001599059,0.005476122,0.0005050848,0.00008560391,0.0002928753,0.001908927,0.0002614201,0.02058379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004467226,"threshold_uncertainty_score":0.01494431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08202481978306725,"score_gpt":0.3002783292946323,"score_spread":0.2182535095115651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}