{"id":"W3175303615","doi":"10.1096/fasebj.2019.33.1_supplement.490.8","title":"A Regulatory Mechanism for Nuclear Lipid Droplet Biogenesis","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Lipid droplet; Endoplasmic reticulum; Chemistry; Cell biology; Biogenesis; Phospholipid; Phosphocholine; Promyelocytic leukemia protein; Biochemistry; Nuclear pore; Cytosol; Biology; Nuclear protein; Phosphatidylcholine; Enzyme; Transcription factor; Cytoplasm; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003538702,0.0005146553,0.0004617221,0.0004703868,0.0008896378,0.001441397,0.0007249459,0.0008824382,0.003602235],"category_scores_gemma":[0.0003930996,0.0003497739,0.0008545133,0.000232159,0.0008122969,0.001373317,0.001047029,0.0008342941,0.002028095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001300749,"about_ca_system_score_gemma":0.000614334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009549547,"about_ca_topic_score_gemma":0.000795158,"domain_scores_codex":[0.9994614,0.00004836181,0.00003269831,0.0002766798,0.0001019697,0.00007894371],"domain_scores_gemma":[0.9996797,0.00002925732,0.00006343692,0.00005437351,0.00009602818,0.00007727459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001922129,0.0000259004,0.000804109,0.0001993968,0.00001532245,0.000467516,0.0001429762,0.0003129551,0.9775831,0.009029978,0.000950958,0.01027577],"study_design_scores_gemma":[0.0001166273,0.0003260605,0.01454225,0.0001231114,0.00005944361,0.001430244,0.0003762901,0.009653133,0.9037744,0.007338686,0.06216956,0.00009016675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5821103,0.07840405,0.2585136,0.007382962,0.003519682,0.0006435463,0.003144767,0.007152278,0.05912878],"genre_scores_gemma":[0.9470265,0.008909904,0.02128492,0.0007910456,0.0003148453,0.0002336617,0.001340027,0.0002326695,0.01986643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003602235,"threshold_uncertainty_score":0.01205069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007877408060315534,"score_gpt":0.2062136028279375,"score_spread":0.198336194767622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}