{"id":"W3175510465","doi":"","title":"Effects of brilliant green on human erythroleukemic K562 and breast adenocarcinoma MCF7 cell growth and on inhibition of human topoisomerase IIα","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"K562 cells; Topoisomerase; Sulforhodamine B; Molecular biology; Growth inhibition; Chemistry; Etoposide; Apoptosis; Flow cytometry; DNA synthesis; Annexin; DNA; Cell culture; Biochemistry; Biology; In vitro; Cytotoxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001425407,0.0004995003,0.0002936932,0.0002794384,0.0001674831,0.0001654605,0.0001396482,0.0002848032,0.001140248],"category_scores_gemma":[0.0001515886,0.0001657673,0.000267479,0.0002067301,0.000182112,0.0001272552,0.0001355295,0.0004230217,0.0002783347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002063455,"about_ca_system_score_gemma":0.0002262895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001667762,"about_ca_topic_score_gemma":0.002715972,"domain_scores_codex":[0.9998679,0.00004174306,0.00001077029,0.00002035992,0.00002942626,0.00002977398],"domain_scores_gemma":[0.9998821,0.00003658987,0.0000177745,0.00001643941,0.0000213735,0.00002581601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000294755,0.00007485068,0.0001333963,0.0000679766,0.000009730826,0.00005298493,0.00002987767,0.00007273911,0.9973655,0.00004587423,0.0001052534,0.001746992],"study_design_scores_gemma":[0.00003316274,0.001013613,0.003376677,0.000011196,0.00002080596,0.0001225055,0.00002707653,0.0003437136,0.9930704,0.00001997985,0.001955532,0.000005198371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889743,0.00607697,0.0008382616,0.0002434767,0.0001043041,0.0000432003,0.0004773215,0.0001019086,0.003140098],"genre_scores_gemma":[0.9871308,0.004139941,0.002400444,0.0001623931,0.00002551295,0.00005896107,0.0009021246,0.00002666594,0.005153134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667762,"threshold_uncertainty_score":0.003814459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03662564262484367,"score_gpt":0.3281743930582514,"score_spread":0.2915487504334077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}