{"id":"W3175515112","doi":"10.1038/s41379-021-00857-z","title":"The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma","year":2021,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Medical Research Council","keywords":"Pathology; Melanoma; Atypical fibroxanthoma; Medicine; Immunohistochemistry; Lentigo maligna; Dermatology; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004198209,0.0002619103,0.0001696097,0.001155871,0.0003473364,0.0008365525,0.0003236231,0.0003216404,0.002600421],"category_scores_gemma":[0.001234346,0.0001888124,0.0001741163,0.0008307208,0.0004531069,0.0005704801,0.0005460336,0.000376509,0.000391641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000233403,"about_ca_system_score_gemma":0.0001953703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008135476,"about_ca_topic_score_gemma":0.001278684,"domain_scores_codex":[0.9997082,0.00005215174,0.00002408203,0.00008010488,0.00006679539,0.00006865548],"domain_scores_gemma":[0.999509,0.0001036714,0.0001832056,0.00005489741,0.00008659941,0.00006252226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005518626,0.00006823961,0.8628486,0.0001278516,0.00007040537,0.0135141,0.0005475627,0.0006755542,0.05821368,0.002842034,0.0009488401,0.05959122],"study_design_scores_gemma":[0.00001308001,0.0001706756,0.8961079,0.00007619113,0.0001131799,0.08301717,0.001485509,0.001282914,0.006064193,0.004186091,0.007466881,0.00001613105],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872684,0.002982098,0.001435376,0.0004867359,0.00001397704,0.00001973482,0.0003624633,0.00003757342,0.007393656],"genre_scores_gemma":[0.9973226,0.0009983216,0.0007540073,0.00008055387,0.00001824926,0.000006205069,0.0003317668,0.00001276497,0.0004755623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002600421,"threshold_uncertainty_score":0.008699298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152705633896288,"score_gpt":0.2493122514187098,"score_spread":0.234041688029081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}