{"id":"W3175618320","doi":"10.1096/fasebj.26.1_supplement.586.1","title":"Differences in susceptibility to nutrient‐induced cell death between primary and immortalized Leigh Syndrome French Canadian type (LSFC) patient fibroblasts","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Necrosis; Lactic acidosis; Apoptosis; Programmed cell death; Internal medicine; Biology; Acidosis; Molecular biology; Endocrinology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032998,0.0002678556,0.0001959931,0.0004857275,0.0004252584,0.0003898677,0.0002449387,0.000336313,0.002873387],"category_scores_gemma":[0.0004187811,0.0001098062,0.0003436805,0.0002938935,0.0002559459,0.0001655345,0.0002498151,0.0003302513,0.0005032432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005699057,"about_ca_system_score_gemma":0.0003487728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02450406,"about_ca_topic_score_gemma":0.02220899,"domain_scores_codex":[0.9997051,0.00002787339,0.00003689794,0.00006996218,0.00008730573,0.00007269617],"domain_scores_gemma":[0.9997751,0.0000647596,0.00003284947,0.00003247277,0.00005061793,0.00004416102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005771436,0.00003627696,0.009583913,0.00006154346,0.00002918839,0.002484436,0.0005411764,0.0001021973,0.9818603,0.0002096759,0.0003431905,0.004170902],"study_design_scores_gemma":[0.00007162511,0.0009562546,0.3982948,0.00004251138,0.0001478458,0.02285034,0.001749038,0.001212617,0.5584047,0.0002152933,0.01598309,0.00007177103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958398,0.0006961263,0.000820432,0.00007561815,0.00001383147,0.00001808402,0.001076969,0.00004224032,0.001416859],"genre_scores_gemma":[0.9956223,0.0004630609,0.0007499024,0.00006617849,0.00000635889,0.00002893896,0.001459832,0.00002294576,0.001580455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02450406,"threshold_uncertainty_score":0.04872286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02205755383855047,"score_gpt":0.2341082317114137,"score_spread":0.2120506778728632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}