{"id":"W3175660796","doi":"10.1096/fasebj.26.1_supplement.1056.6","title":"Lung endothelial Ca <sup>2+</sup> and permeability response to PAF is mediated by TRPC6","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"TRPC6; Vascular permeability; Ceramide; Caveolae; Cell biology; Pulmonary edema; Lung; Chemistry; Platelet-activating factor; Endothelium; Transient receptor potential channel; Internal medicine; Endocrinology; Signal transduction; Biology; Medicine; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002534778,0.0003661701,0.0003598685,0.000216254,0.0001601744,0.0003986708,0.0002141432,0.0004734669,0.001489353],"category_scores_gemma":[0.0002513959,0.0002256643,0.0004104185,0.0001216733,0.0003417978,0.0004170823,0.0002103453,0.0009061892,0.0003483835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003001118,"about_ca_system_score_gemma":0.0001618483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004229429,"about_ca_topic_score_gemma":0.0003567402,"domain_scores_codex":[0.9997578,0.0000468661,0.00002073357,0.00003429994,0.00007323743,0.00006699355],"domain_scores_gemma":[0.999833,0.00002256486,0.00005644989,0.00002178663,0.00002483595,0.00004138668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002046658,0.00001023595,0.00010922,0.00001745076,0.00000345317,0.00004315394,0.000004069803,0.00002996776,0.9991438,0.00003997751,0.00002339628,0.0003704905],"study_design_scores_gemma":[0.00002384869,0.0001832144,0.007264875,0.000003939203,0.0000155838,0.0003387296,0.00001932387,0.001207095,0.9901482,0.00009184091,0.0006986981,0.000004615526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926434,0.001651622,0.003783459,0.0003162264,0.00003653249,0.00002338902,0.000348207,0.0001268166,0.00107026],"genre_scores_gemma":[0.9962924,0.0006184665,0.001818859,0.00006997635,0.00001829939,0.00003684756,0.0002405968,0.00001865935,0.0008858481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001489353,"threshold_uncertainty_score":0.004982352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02183051692574114,"score_gpt":0.2661348194081682,"score_spread":0.244304302482427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}