{"id":"W3175747586","doi":"10.4049/jimmunol.2100421","title":"Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; University of Minnesota; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Spike (software development); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Immunity; Spike Protein; 2019-20 coronavirus outbreak; Biology; Medicine; Immunology; Immune system; Computer science; Infectious disease (medical specialty); Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062343,0.0002483147,0.0006973009,0.0002913233,0.0002810463,0.00003571627,0.0005983462,0.000230021,0.00004425357],"category_scores_gemma":[0.001572234,0.0001661373,0.0002701811,0.000568564,0.0001596488,0.0001619323,0.0004036391,0.002285831,0.0001286154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058314,"about_ca_system_score_gemma":0.0009344831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002643875,"about_ca_topic_score_gemma":0.00005687405,"domain_scores_codex":[0.9970718,0.0008152359,0.0008006084,0.0001968692,0.000546306,0.0005691631],"domain_scores_gemma":[0.9970274,0.0004248281,0.0005083078,0.000705384,0.001302385,0.00003171813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002158205,0.0003538458,0.001759113,0.00004454326,0.0007182899,0.0006869743,0.001238265,9.077005e-7,0.9806722,0.00009435998,0.0003538413,0.0119194],"study_design_scores_gemma":[0.003678124,0.00134311,0.01811326,0.0002208072,0.0002016378,0.01029171,0.002139085,0.00003683648,0.9459349,0.0008841043,0.01700434,0.0001521178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859332,0.007006027,0.0004969368,0.003363784,0.0004850269,0.0003665408,0.000001972067,0.00003007067,0.002316431],"genre_scores_gemma":[0.9875319,0.0001707304,0.0001964413,0.01159128,0.0004009824,0.000008666608,8.68057e-7,0.00004415727,0.00005498866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03473739,"threshold_uncertainty_score":0.9930926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03915850643159725,"score_gpt":0.3449155035547778,"score_spread":0.3057569971231806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}