{"id":"W3175803552","doi":"10.2139/ssrn.3874014","title":"Safety and Immunogenicity Report from the Com-COV Study – a Single-Blind Randomised Non-Inferiority Trial Comparing Heterologous And Homologous Prime-Boost Schedules with An Adenoviral Vectored and mRNA COVID-19 Vaccine","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Reactogenicity; Medicine; Immunogenicity; Heterologous; Confidence interval; Population; Modified vaccinia Ankara; Randomized controlled trial; Vaccination; Internal medicine; Immunology; Immune system; Vaccinia; Recombinant DNA; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00548765,0.002234077,0.004615731,0.0004786932,0.0005806557,0.001382053,0.0008201548,0.003637842,0.01158473],"category_scores_gemma":[0.00430799,0.001080833,0.003945517,0.0005149439,0.001853258,0.001578274,0.0004460245,0.004187156,0.002280812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006708094,"about_ca_system_score_gemma":0.001339486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005931805,"about_ca_topic_score_gemma":0.000648835,"domain_scores_codex":[0.9972665,0.001568662,0.0002656842,0.0003657421,0.0002269042,0.0003064429],"domain_scores_gemma":[0.9967068,0.001304879,0.000722049,0.0004879091,0.0003086677,0.0004697267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9809111,0.004276228,0.0002944188,0.0006260575,0.00139519,0.00003572806,0.00003804923,0.0002062091,0.003796707,0.0001075698,0.0008779222,0.007434794],"study_design_scores_gemma":[0.9151019,0.07916507,0.00198571,0.00005589004,0.001092015,0.00004125651,0.00001808415,0.000202898,0.0009188529,0.0002380015,0.001154909,0.00002540123],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9602216,0.007053157,0.004358853,0.001437512,0.001680067,0.01216739,0.005723981,0.0002961037,0.007061361],"genre_scores_gemma":[0.9673532,0.002947213,0.003754519,0.001978057,0.001217509,0.01116005,0.00367902,0.0001430266,0.007767379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01158473,"threshold_uncertainty_score":0.03875476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05639156308647435,"score_gpt":0.3490973046203508,"score_spread":0.2927057415338765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}