{"id":"W3175803926","doi":"10.3390/pathophysiology28030021","title":"A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage","year":2021,"lang":"en","type":"article","venue":"Pathophysiology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University; London Health Sciences Centre; Lawson Health Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Synovial fluid; Elastase; Cathepsin G; Proteinase 3; Arthritis; Myeloperoxidase; Chemistry; Cathepsin; Neutrophil elastase; Cartilage; Molecular biology; Immunology; Internal medicine; Medicine; Pathology; Osteoarthritis; Inflammation; Biochemistry; Enzyme; Biology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003930353,0.000155908,0.0006343184,0.00008895555,0.0001519554,0.00001599255,0.00008474659,0.0001925887,0.0003411956],"category_scores_gemma":[0.001763345,0.0001532688,0.0001384475,0.0004135616,0.00006649495,0.00006386561,0.0001347996,0.0003260391,0.0006135688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001234432,"about_ca_system_score_gemma":0.0004898419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002183909,"about_ca_topic_score_gemma":0.00003828894,"domain_scores_codex":[0.998147,0.0003370586,0.000413095,0.0003767898,0.0002171736,0.0005089138],"domain_scores_gemma":[0.9987954,0.00003548916,0.00008664091,0.0004378974,0.0004614909,0.0001830047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001968519,0.0002687618,0.0006907336,0.00005146664,0.00002213063,0.001189161,0.0001931899,0.000005789048,0.9910856,0.0003497632,0.0007910542,0.005155526],"study_design_scores_gemma":[0.01100804,0.003669403,0.1434702,0.001095489,0.00009649081,0.0001516102,0.000747084,0.0005142427,0.8017465,0.004721181,0.03195174,0.0008280849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946575,0.002036436,0.0001453279,0.001684522,0.0001152033,0.0006571934,0.00002991477,0.0001025717,0.0005713662],"genre_scores_gemma":[0.9965806,0.0001705341,0.00009845883,0.001540352,0.00009018557,0.0002277779,0.0002227379,0.00002464286,0.001044736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1893391,"threshold_uncertainty_score":0.7886389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211282065940984,"score_gpt":0.2742720578209992,"score_spread":0.2621592371615893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}