{"id":"W3175888909","doi":"10.1096/fasebj.25.1_supplement.1059.13","title":"Mitochondrial biogenesis elicited by chronic contractile activity with mTORC1 inhibition","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"mTORC1; Mitochondrial biogenesis; Biogenesis; Cell biology; Chemistry; Mitochondrion; Biology; Signal transduction; Biochemistry; PI3K/AKT/mTOR pathway; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002393003,0.000510932,0.0006979267,0.0001922477,0.0002395717,0.0003027762,0.0002393555,0.0003181084,0.001424041],"category_scores_gemma":[0.0001303851,0.0001766457,0.0004443304,0.0002284566,0.0004404077,0.0002441606,0.0004194113,0.001084476,0.0002812677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003180478,"about_ca_system_score_gemma":0.0004145466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008605702,"about_ca_topic_score_gemma":0.001902009,"domain_scores_codex":[0.9997317,0.00003590836,0.00003178108,0.0000528469,0.00004129918,0.0001063083],"domain_scores_gemma":[0.9998519,0.00001727608,0.00003921141,0.00001855246,0.00001736037,0.00005562121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00140161,0.0001215706,0.0002424437,0.0001251406,0.000017353,0.00008837206,0.00002567933,0.00005555863,0.9961938,0.00006698501,0.0001683463,0.001493316],"study_design_scores_gemma":[0.0001463872,0.002996305,0.01643062,0.00003105974,0.00006840084,0.000270158,0.0000894023,0.001111269,0.974794,0.00006130307,0.003985658,0.00001539056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934583,0.002549412,0.001531373,0.0002192507,0.0001325282,0.0000724659,0.0006247884,0.0001079018,0.001304069],"genre_scores_gemma":[0.9927376,0.001440399,0.001550709,0.0001553312,0.00006358392,0.0002507087,0.001324666,0.00003083045,0.002446157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424041,"threshold_uncertainty_score":0.004763901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054508737562744,"score_gpt":0.214186044400914,"score_spread":0.2036409570252865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}