{"id":"W3175919488","doi":"10.1096/fasebj.22.1_supplement.1050.3","title":"Opposite Regulation of Human D1‐like Dopaminergic Responsiveness by Protein Kinase C is Shaped by Two Critical Serine Residues of the Third Intracellular Loop of Human D5 Dopaminergic Receptor","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Serine; Biology; Activator (genetics); Receptor; Dopaminergic; Molecular biology; Phosphorylation; Biochemistry; Dopamine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008160543,0.0001968827,0.0001213256,0.00008305674,0.00009906437,0.0001889428,0.0001282151,0.0001734421,0.0009995793],"category_scores_gemma":[0.000120421,0.000088466,0.0002474182,0.00008480845,0.0001673924,0.00008504023,0.0001153309,0.0003299907,0.0003516595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003676181,"about_ca_system_score_gemma":0.0001807633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004331275,"about_ca_topic_score_gemma":0.000550878,"domain_scores_codex":[0.9999025,0.00001754743,0.00001022886,0.00002327339,0.00001895494,0.00002742469],"domain_scores_gemma":[0.999912,0.00001977565,0.00002968253,0.00001078316,0.000005832031,0.00002193936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002295798,0.0000116566,0.0001999429,0.00001220773,0.000002575323,0.00004260981,0.000008168041,0.00005340539,0.9990411,0.00005522323,0.000008682546,0.0003347538],"study_design_scores_gemma":[0.00003632881,0.0001964599,0.008750791,0.00000354641,0.000009498154,0.000367828,0.00002570594,0.0009765066,0.9887919,0.0000380131,0.0007977246,0.000005679406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989366,0.0002066742,0.0004539613,0.00002264037,0.000005711263,0.000006774258,0.0000910818,0.000008997529,0.0002675213],"genre_scores_gemma":[0.9983367,0.0001850419,0.0006581959,0.00002430816,0.000002475341,0.00001284103,0.0002785482,0.000004464485,0.0004975009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009995793,"threshold_uncertainty_score":0.00334388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364419642615088,"score_gpt":0.2551610731656133,"score_spread":0.2415168767394624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}