{"id":"W3175948559","doi":"10.1096/fasebj.22.1_supplement.386.8","title":"Cardiac restricted overexpression of E2F6 alters cell cycle dynamics and results in dilated cardiomyopathy in mice","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Dilated cardiomyopathy; Cell cycle; Histone; Chemistry; Biology; Molecular biology; Internal medicine; Cell biology; Endocrinology; Biochemistry; Apoptosis; Medicine; Heart failure; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000296978,0.0005270776,0.000299425,0.0006673742,0.0002050927,0.0002947477,0.0002601309,0.0005981164,0.001664638],"category_scores_gemma":[0.0001221745,0.0003086628,0.0003319872,0.0001996305,0.0004104591,0.0002466913,0.0002116905,0.0006662104,0.0006327285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003019155,"about_ca_system_score_gemma":0.00016213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005010222,"about_ca_topic_score_gemma":0.001046997,"domain_scores_codex":[0.9997982,0.00003541407,0.00002468719,0.00005230497,0.0000378422,0.00005153174],"domain_scores_gemma":[0.9998091,0.00003305703,0.00007270228,0.00001855545,0.00001062852,0.00005598176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001465087,0.00004772621,0.0001989304,0.00001654346,0.000004697928,0.00007037399,0.00001251138,0.00005237292,0.9986255,0.00008837641,0.00002982418,0.0007066044],"study_design_scores_gemma":[0.00009970013,0.0005631197,0.008711614,0.00001518381,0.00003965374,0.0005964491,0.00003147756,0.0008319913,0.9862736,0.0001129885,0.002715663,0.000008520019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924362,0.001143134,0.003494266,0.0001790673,0.00003269319,0.00005159459,0.0009282561,0.0002174085,0.001517325],"genre_scores_gemma":[0.984963,0.001509449,0.004001084,0.0001627638,0.00002237184,0.0001129529,0.001262276,0.0001196723,0.00784642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001664638,"threshold_uncertainty_score":0.005568743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008039511586039333,"score_gpt":0.2218183786692469,"score_spread":0.2137788670832075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}