{"id":"W3176060870","doi":"10.1096/fasebj.2018.32.1_supplement.572.3","title":"Effect of Hypoxia on Macrophage MMP‐2 expression: Role of O2 availability in Determining Atherosclerotic Plaque Stability","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Saskatchewan Health Research Foundation","keywords":"Medicine; Asymptomatic; Fibrous cap; Carotid endarterectomy; Pathology; Stroke (engine); Matrix metalloproteinase; Vulnerable plaque; Hypoxia (environmental); Thrombus; Thrombosis; Peripheral blood mononuclear cell; Immunohistochemistry; Internal medicine; Stenosis; Biology; Chemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002260222,0.0001730058,0.0002739164,0.0001072853,0.0001918183,0.0002225233,0.0001123276,0.0002013479,0.0009946404],"category_scores_gemma":[0.000161546,0.0001101161,0.0002000531,0.00008110317,0.0002340724,0.000188635,0.0001641095,0.0002594443,0.0001305158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001671101,"about_ca_system_score_gemma":0.0001779646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001120512,"about_ca_topic_score_gemma":0.001441276,"domain_scores_codex":[0.9998547,0.00004273159,0.000009777883,0.00002508723,0.00002159538,0.00004609744],"domain_scores_gemma":[0.9998765,0.00002756815,0.00002897204,0.00001202486,0.00001835335,0.00003660262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002338787,0.0001301439,0.003552988,0.00009135011,0.00001579204,0.0001167933,0.00008963965,0.00004341682,0.9915509,0.00002946225,0.00006307333,0.00197762],"study_design_scores_gemma":[0.00008125867,0.00405517,0.1457172,0.00002623771,0.0000795802,0.0005484623,0.0003318515,0.001170767,0.8458983,0.00012618,0.001949239,0.00001577719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966979,0.001969799,0.0004347507,0.0001010313,0.00002558667,0.00001593585,0.0001149623,0.000005506012,0.000634635],"genre_scores_gemma":[0.9971493,0.0009200586,0.000698179,0.00007058025,0.00002610877,0.0000441867,0.0001477271,0.000002845176,0.00094111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120512,"threshold_uncertainty_score":0.003327429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009625960420487772,"score_gpt":0.241192107165089,"score_spread":0.2315661467446012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}