{"id":"W3176208875","doi":"10.1056/nejmoa2107322","title":"Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer","year":2021,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2598,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; National Institute for Health and Care Research; Advanced Accelerator Applications; Endocyte; Novartis","keywords":"Prostate cancer; Medicine; Castration; Oncology; Cancer research; Prostate; Internal medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000383519,0.0001861702,0.0004470599,0.0002157198,0.0001566328,0.0002538442,0.0002195551,0.0001808459,0.002803976],"category_scores_gemma":[0.0003483184,0.00006235289,0.0003372158,0.0001936063,0.000202225,0.0001754377,0.0001437506,0.0004405286,0.000371129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007348536,"about_ca_system_score_gemma":0.0007518578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001192429,"about_ca_topic_score_gemma":0.00577794,"domain_scores_codex":[0.9999034,0.00003408319,0.000005514714,0.00001220933,0.00002714463,0.00001763366],"domain_scores_gemma":[0.9998806,0.00002643932,0.00003029768,0.000007292527,0.000009101596,0.00004635972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.05928057,0.004645857,0.01686636,0.002243117,0.0009199832,0.0008811054,0.0002448597,0.002945211,0.1247923,0.001017132,0.01147842,0.7746852],"study_design_scores_gemma":[0.05824223,0.2851656,0.4239961,0.0007575004,0.003018302,0.01060779,0.0004228003,0.01253615,0.09206755,0.002381541,0.1106471,0.0001573119],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668233,0.02578452,0.0006871584,0.001088741,0.000126869,0.0002707938,0.0002666233,0.0001399043,0.004812095],"genre_scores_gemma":[0.9949644,0.002914299,0.0004350564,0.0002197751,0.00005322877,0.00004469097,0.0002041345,0.000008480511,0.001155974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002803976,"threshold_uncertainty_score":0.009380281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0572078347326491,"score_gpt":0.3764620238311657,"score_spread":0.3192541890985165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}