{"id":"W3176394553","doi":"10.1001/jamanetworkopen.2021.15312","title":"Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features","year":2021,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Medicine; Prostate cancer; Androgen deprivation therapy; Brachytherapy; Prostatectomy; External beam radiotherapy; Interquartile range; Common Terminology Criteria for Adverse Events; Oncology; Internal medicine; Cancer; Retrospective cohort study; Cohort; Multimodal therapy; Hazard ratio; Radiation therapy; Urology; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009355418,0.00019664,0.0003174776,0.0004133476,0.0002349151,0.0004235146,0.0004345758,0.0003645261,0.001629625],"category_scores_gemma":[0.002285511,0.0001515499,0.0005886817,0.0005563738,0.0002057444,0.000452617,0.0004689771,0.0004292727,0.0001680524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000487475,"about_ca_system_score_gemma":0.0003926913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366305,"about_ca_topic_score_gemma":0.002852335,"domain_scores_codex":[0.9993123,0.0002123147,0.00007169932,0.0001884506,0.000118758,0.00009643617],"domain_scores_gemma":[0.998613,0.0002254718,0.0008141075,0.00009225131,0.00008003857,0.0001751081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004913755,0.00004773968,0.9966369,0.00001478489,0.0002200094,0.00002850811,0.00001569244,0.0001998897,0.0001114101,0.00002771247,0.0001218548,0.002084161],"study_design_scores_gemma":[0.00006984449,0.0005063254,0.9976293,0.00001163119,0.0001328981,0.0002723178,0.00008974523,0.0008176807,0.0001135941,0.00009745283,0.0002526607,0.000006386029],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986314,0.000412191,0.0001552919,0.00005289981,0.000006507007,0.000009331388,0.0004061223,0.000002405798,0.0003238331],"genre_scores_gemma":[0.9992132,0.00006856123,0.00006075365,0.00002601398,0.00001144096,0.000008091993,0.0005382326,0.000001184527,0.00007246871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001629625,"threshold_uncertainty_score":0.00545162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599014522955538,"score_gpt":0.3158916893401532,"score_spread":0.2999015441105978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}