{"id":"W3176534222","doi":"10.1096/fasebj.26.1_supplement.696.10","title":"Active transepithelial Cl <sup>−</sup> ‐secretion promotes hydrostatic lung edema","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Epithelial sodium channel; Hydrostatic pressure; Cystic fibrosis transmembrane conductance regulator; Chemistry; Secretion; Bumetanide; Reabsorption; Edema; Lung; Amiloride; Internal medicine; Endocrinology; Pulmonary edema; Transepithelial potential difference; Cystic fibrosis; Cotransporter; Kidney; Ion transporter; Sodium; Biology; Biochemistry; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002282776,0.0002983743,0.0003771936,0.0002860855,0.0001385381,0.0005381038,0.0001820063,0.0003531877,0.001373784],"category_scores_gemma":[0.0001855982,0.0001781135,0.0002634299,0.0001249422,0.0006170662,0.0004769535,0.0002877498,0.0007887498,0.0003942423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574152,"about_ca_system_score_gemma":0.0001592625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001909291,"about_ca_topic_score_gemma":0.0001914695,"domain_scores_codex":[0.9997842,0.00004569245,0.00002244896,0.0000361696,0.00005456142,0.00005701005],"domain_scores_gemma":[0.9996725,0.00004475359,0.0001212949,0.00003116953,0.00003004777,0.0001001923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001661462,0.00001722944,0.0002365866,0.00001778082,0.000002467986,0.0001189796,0.000008247682,0.00001547181,0.9988728,0.00006108933,0.00002361247,0.0004595883],"study_design_scores_gemma":[0.0000328413,0.000344744,0.01665357,0.00000771199,0.00001496085,0.000967585,0.00006706523,0.0008842406,0.9796426,0.0002053901,0.001172946,0.000006443019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947757,0.001609851,0.002465285,0.0002462055,0.00003797383,0.00001147053,0.0001105123,0.0001055455,0.0006375205],"genre_scores_gemma":[0.9977484,0.0005239796,0.0006626042,0.00007454482,0.00002519092,0.00001484886,0.00009269753,0.00001459741,0.0008430918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001373784,"threshold_uncertainty_score":0.004595816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00971724268555363,"score_gpt":0.2346032110184736,"score_spread":0.22488596833292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}