{"id":"W3176689297","doi":"10.1096/fasebj.2019.33.1_supplement.845.6","title":"Ca <sup>2+</sup> Signaling and Barrier Function of Lung Microvascular Endothelial Cells are Modulated by Mesenchymal Stromal Cell Microparticles","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"ARDS; Mesenchymal stem cell; Microvesicle; Extracellular; Thrombin; Microvesicles; Intracellular; Cell biology; Endothelial stem cell; Stromal cell; Chemistry; Medicine; Vascular permeability; Cancer research; Lung; Pathology; Platelet; Immunology; Biology; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553339,0.0003162918,0.000262985,0.0001664303,0.0001077599,0.0004078821,0.0001440982,0.0003135964,0.001067156],"category_scores_gemma":[0.0001359314,0.0001046757,0.000278848,0.0001449429,0.0001948128,0.0001949163,0.0001470936,0.000325936,0.0003331438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002100354,"about_ca_system_score_gemma":0.0001491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004829245,"about_ca_topic_score_gemma":0.0003792824,"domain_scores_codex":[0.9998226,0.00003438706,0.00002359395,0.00002390542,0.00004511205,0.00005057415],"domain_scores_gemma":[0.9999048,0.00001951402,0.00002923373,0.000006925935,0.00001462439,0.00002490479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003032776,0.00002219911,0.0002352359,0.00005440191,0.000006587024,0.00008524719,0.0000116066,0.0000359062,0.9981741,0.00004925544,0.00005354515,0.000968712],"study_design_scores_gemma":[0.00004630456,0.0003607968,0.01723129,0.00001041285,0.00003014222,0.0004372522,0.00005511939,0.001113934,0.9784614,0.00007921886,0.002167924,0.000006209287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908332,0.004577748,0.002236685,0.0002293162,0.00005464703,0.00002756339,0.0004692646,0.00007478322,0.001496771],"genre_scores_gemma":[0.9965177,0.001035084,0.001037984,0.00009407811,0.00001688946,0.00004669242,0.0002921312,0.00001017069,0.0009492771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001067156,"threshold_uncertainty_score":0.00357002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003349507906071653,"score_gpt":0.1858394657459418,"score_spread":0.1824899578398701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}