{"id":"W3176887844","doi":"10.1096/fasebj.25.1_supplement.941.6","title":"Kaposi¡s sarcoma‐associated herpesvirus degrades cellular TIR‐domain‐containing adaptor‐inducing beta interferon (TRIF)","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"TRIF; Signal transducing adaptor protein; Ubiquitin ligase; Innate immune system; Cell biology; Ubiquitin; Lytic cycle; Interferon; Biology; Proteasome; Signal transduction; Virology; Toll-like receptor; Virus; Immunology; Immune system; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001664603,0.0003973029,0.0001806005,0.0001921729,0.000104619,0.0002295247,0.00009592671,0.000178661,0.00112314],"category_scores_gemma":[0.0001159889,0.0001067653,0.0002612944,0.00007104399,0.0001168554,0.0002102356,0.0001734556,0.0003371599,0.0005083852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001829274,"about_ca_system_score_gemma":0.0001251873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001574131,"about_ca_topic_score_gemma":0.0001934124,"domain_scores_codex":[0.9998734,0.00002237155,0.00001213003,0.00002264111,0.00003031625,0.00003918664],"domain_scores_gemma":[0.9999102,0.00001266497,0.0000318173,0.00001316712,0.00001184302,0.00002032844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008646548,0.00001324757,0.0001939817,0.00003727011,0.000004979114,0.00004257419,0.000006323925,0.00003603947,0.9975826,0.00009823402,0.00004797653,0.001850262],"study_design_scores_gemma":[0.00001112926,0.0002012272,0.006382351,0.000006852561,0.00001208143,0.0008497247,0.00001847029,0.0006447747,0.989055,0.00007928876,0.002734629,0.000004501628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869969,0.004781983,0.005049249,0.00009184804,0.00005094476,0.00002032746,0.0004206247,0.0001348763,0.002453304],"genre_scores_gemma":[0.9925189,0.00156479,0.002133269,0.00004727144,0.0000152693,0.00001622772,0.0006605465,0.00001278733,0.003030894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112314,"threshold_uncertainty_score":0.003757238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04178714154233752,"score_gpt":0.2381914668839858,"score_spread":0.1964043253416483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}