{"id":"W3176913979","doi":"10.1177/23814683211021060","title":"Real-World Cost-Effectiveness of Bevacizumab With First-Line Combination Chemotherapy in Patients With Metastatic Colorectal Cancer: Population-Based Retrospective Cohort Studies in Three Canadian Provinces","year":2021,"lang":"en","type":"article","venue":"MDM Policy & Practice","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Partnership Against Cancer; Sunnybrook Health Science Centre; Alberta Cancer Foundation; Simon Fraser University; Institute for Clinical Evaluative Sciences; Cancer Care Ontario; St. Michael's Hospital; Saskatchewan Cancer Agency; Canadian Centre for Applied Research in Cancer Control","funders":"","keywords":"Bevacizumab; Medicine; Irinotecan; Colorectal cancer; Oncology; Internal medicine; Propensity score matching; Population; Cost effectiveness; Retrospective cohort study; Chemotherapy; Surgery; Cancer; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003761193,0.0009411984,0.001164806,0.002392146,0.002426272,0.002050834,0.002746307,0.0007842313,0.001688058],"category_scores_gemma":[0.009804705,0.0008808026,0.003325851,0.009116204,0.001279515,0.0005047082,0.001250341,0.001284355,0.0001705799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.06343716,"about_ca_system_score_gemma":0.05587114,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9934098,"about_ca_topic_score_gemma":0.9933073,"domain_scores_codex":[0.9966265,0.0006262476,0.0004266721,0.0006256115,0.0007968476,0.0008982255],"domain_scores_gemma":[0.9898335,0.001372039,0.003368466,0.001013327,0.002946439,0.001466268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006069327,0.00006021969,0.9908478,0.0001380222,0.001327248,0.0001800908,0.0003495232,0.001804744,0.00008602018,0.0003127037,0.00164274,0.002643943],"study_design_scores_gemma":[0.0002070957,0.00009433916,0.9919471,0.0001283447,0.0009393513,0.0002350895,0.0008937549,0.003643904,0.00009867556,0.0001436554,0.001590547,0.0000780897],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762979,0.001716881,0.0005579992,0.0004221026,0.00002337691,0.0001971826,0.01959776,0.0000238754,0.001162959],"genre_scores_gemma":[0.9927976,0.0007195556,0.0005924754,0.0001378457,0.0000103755,0.00009158577,0.005411577,0.00001019311,0.0002287461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06343716,"threshold_uncertainty_score":0.460271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02602121183618887,"score_gpt":0.3597646630281316,"score_spread":0.3337434511919428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}