{"id":"W3176913979","doi":"10.1177/23814683211021060","title":"Real-World Cost-Effectiveness of Bevacizumab With First-Line Combination Chemotherapy in Patients With Metastatic Colorectal Cancer: Population-Based Retrospective Cohort Studies in Three Canadian Provinces","year":2021,"lang":"en","type":"article","venue":"MDM Policy & Practice","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Partnership Against Cancer; Sunnybrook Health Science Centre; Alberta Cancer Foundation; Simon Fraser University; Institute for Clinical Evaluative Sciences; Cancer Care Ontario; St. Michael's Hospital; Saskatchewan Cancer Agency; Canadian Centre for Applied Research in Cancer Control","funders":"","keywords":"Bevacizumab; Medicine; Irinotecan; Colorectal cancer; Oncology; Internal medicine; Propensity score matching; Population; Cost effectiveness; Retrospective cohort study; Chemotherapy; Surgery; Cancer; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003534177,0.0002450575,0.0007266682,0.000420417,0.0001165,0.00001622474,0.00005027129,0.00003775823,0.00001636339],"category_scores_gemma":[0.0008147295,0.0001851972,0.00003730576,0.001438644,0.0001356246,0.0002454038,0.00001690981,0.000183051,5.199192e-7],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006797754,"about_ca_system_score_gemma":0.002631809,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.7422533,"about_ca_topic_score_gemma":0.9705216,"domain_scores_codex":[0.998337,0.0002158426,0.0003142596,0.0003944216,0.0004309663,0.0003075649],"domain_scores_gemma":[0.9977442,0.0008440384,0.0002787647,0.0001799301,0.0008633852,0.00008968517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008268322,0.000974321,0.986728,0.0002494866,0.0009492108,0.00008587677,0.0007541928,0.0004344739,0.000004960267,0.0003741558,0.000006777223,0.001170217],"study_design_scores_gemma":[0.01118874,0.002058207,0.9844477,0.0006496873,0.0003824652,0.000004231554,0.0002800885,0.0001118881,0.0004737304,0.0001724264,0.00005424151,0.0001766012],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925894,0.0003214722,0.00000533015,0.002946148,0.00005014978,0.002639889,0.00008878911,0.00001726983,0.001341597],"genre_scores_gemma":[0.9981147,0.0003421831,0.0002755621,0.0001997763,0.00002453021,0.0008492597,0.000126275,0.00003042963,0.00003728215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2282683,"threshold_uncertainty_score":0.997015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02602121183618887,"score_gpt":0.3597646630281316,"score_spread":0.3337434511919428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}