{"id":"W3176923522","doi":"10.1096/fasebj.2019.33.1_supplement.538.2","title":"Reduced Extracellular [Ca 2+ ] Increases the Sensitivity of Mouse EDL and Soleus to the K + ‐Induced Force Depression: Implication for the Increased Sensitivity of Hyperkalemic Periodic Paralysis Muscles to Calcium Levels","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Internal medicine; Salbutamol; Endocrinology; Extracellular; Soleus muscle; Calcium; Biophysics; Skeletal muscle; Biochemistry; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002459478,0.0004969058,0.0006185083,0.0003802005,0.0001948187,0.0004345271,0.0005922009,0.0009125802,0.002002912],"category_scores_gemma":[0.0002715706,0.0004336358,0.0004404782,0.0001867879,0.0006178262,0.0003900638,0.0003505427,0.001277401,0.0003835922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004530872,"about_ca_system_score_gemma":0.000259913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001028546,"about_ca_topic_score_gemma":0.001838162,"domain_scores_codex":[0.9996718,0.0000511602,0.00007188262,0.00005007392,0.00007193322,0.00008315055],"domain_scores_gemma":[0.999493,0.00007849748,0.000155623,0.00004370198,0.00005377532,0.0001754108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003747907,0.00002879547,0.00009531571,0.000028485,0.000004866233,0.00004489956,0.00001065559,0.00001730369,0.9992404,0.00001835949,0.0000109533,0.0001251508],"study_design_scores_gemma":[0.0001251669,0.001205759,0.01017327,0.00001129919,0.00003151146,0.0002133294,0.00006778698,0.0003634906,0.9869716,0.00005554203,0.0007682836,0.0000129959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977685,0.0005835334,0.0004524608,0.0001919134,0.00003307336,0.00002860258,0.0003810983,0.00005978956,0.0005009791],"genre_scores_gemma":[0.994766,0.0004410436,0.001412068,0.0002728531,0.00002019924,0.0001238286,0.0005294543,0.00003467426,0.00239989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002002912,"threshold_uncertainty_score":0.006700456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286800611835452,"score_gpt":0.2589298950558901,"score_spread":0.2360618889375356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}