{"id":"W3176923618","doi":"10.1136/rmdopen-2021-001660","title":"Hydroxychloroquine in patients with inflammatory and erosive osteoarthritis of the hands: results of the OA-TREAT study—a randomised, double-blind, placebo-controlled, multicentre, investigator-initiated trial","year":2021,"lang":"en","type":"article","venue":"RMD Open","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung","keywords":"Medicine; Placebo; Osteoarthritis; Adverse effect; Clinical endpoint; Physical therapy; Hydroxychloroquine; Randomized controlled trial; Internal medicine; Disease; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003241907,0.00139959,0.003702619,0.0004512306,0.0004235588,0.001087809,0.0007360094,0.002835614,0.005221721],"category_scores_gemma":[0.002921981,0.00063126,0.002509924,0.0004435088,0.0009013274,0.001143298,0.000337326,0.00187232,0.0007290377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004440969,"about_ca_system_score_gemma":0.0007742875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005087475,"about_ca_topic_score_gemma":0.001122738,"domain_scores_codex":[0.9985716,0.0008961664,0.000104276,0.0001681233,0.0001324897,0.0001272382],"domain_scores_gemma":[0.9984273,0.0005178581,0.000418938,0.0001052279,0.0001363681,0.0003943316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9757956,0.004733291,0.0008601716,0.001619048,0.001374736,0.00006460442,0.00005899237,0.0001283536,0.002527475,0.00006834208,0.0006032148,0.01216631],"study_design_scores_gemma":[0.9684488,0.02898001,0.001672898,0.00004239745,0.0003238115,0.00002344097,0.000009988775,0.00007995521,0.00008267905,0.00003025776,0.0002986932,0.000007114867],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9589101,0.02937717,0.0006345531,0.001032072,0.0008547991,0.005114762,0.001213269,0.00009373419,0.002769508],"genre_scores_gemma":[0.9736419,0.01095361,0.001569052,0.001983651,0.001554369,0.006022837,0.001381261,0.00002333235,0.002870038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005221721,"threshold_uncertainty_score":0.01746839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02392067448828364,"score_gpt":0.2632701691185669,"score_spread":0.2393494946302832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}