{"id":"W3177015589","doi":"10.1186/s12891-021-04467-3","title":"Safety and efficacy of single CHAP Hyaluronan injection versus three injections of linear Hyaluronan in pain relief for knee osteoarthritis: a prospective, 52-week follow-up, randomized, evaluator-blinded study","year":2021,"lang":"en","type":"article","venue":"BMC Musculoskeletal Disorders","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; Sports medicine; Rheumatology; Viscosupplementation; Physical therapy; Randomized controlled trial; Orthopedic surgery; Pain relief; Hyaluronic acid; Surgery; Internal medicine; Intra articular; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00140561,0.0004026449,0.00122743,0.000373211,0.0001690639,0.00001690007,0.00008208775,0.000196058,0.00004433746],"category_scores_gemma":[0.002868952,0.0003923441,0.0006792619,0.0007030905,0.0002567196,0.0001638114,0.00008878149,0.0002213825,0.000002755603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001325663,"about_ca_system_score_gemma":0.0003382074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002235969,"about_ca_topic_score_gemma":0.01435307,"domain_scores_codex":[0.9967198,0.0006019139,0.0009796944,0.0007423739,0.0005267852,0.0004294078],"domain_scores_gemma":[0.997648,0.001091031,0.0003069691,0.0004749554,0.0003436511,0.0001354073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3178473,0.01368229,0.05904674,0.001095096,0.0008381461,0.0000184771,0.003706482,0.000222086,0.003557218,0.001465974,0.000007238058,0.598513],"study_design_scores_gemma":[0.8063189,0.1259944,0.05535759,0.0005776188,0.001266691,0.00001559955,0.007502083,0.0007078869,0.0005079637,0.001142881,0.00008515787,0.0005232187],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987469,0.001683011,0.001798324,0.00005277834,0.0006014156,0.007568644,0.00004131407,0.00007483381,0.0007106377],"genre_scores_gemma":[0.9968613,0.00003190462,0.001811867,0.00001211098,0.00007787714,0.0007679538,0.0001392512,0.00007392277,0.0002237616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5979898,"threshold_uncertainty_score":0.9998528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02312026193544026,"score_gpt":0.2889540859082733,"score_spread":0.265833823972833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}