{"id":"W3177112330","doi":"10.1210/endrev/bnab021","title":"The β Cell in Diabetes: Integrating Biomarkers With Functional Measures","year":2021,"lang":"en","type":"review","venue":"Endocrine Reviews","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Juvenile Diabetes Research Foundation United States of America; University of Washington; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; National Institutes of Health; VA Puget Sound Health Care System","keywords":"Disease; Diabetes mellitus; Biomarker; Pathological; Bioinformatics; Function (biology); Immune system; Pathogenesis; Medicine; Cell; Biology; Computational biology; Immunology; Pathology; Endocrinology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00179278,0.001281824,0.002325513,0.002890988,0.0002866578,0.001898933,0.001190731,0.00181737,0.002912937],"category_scores_gemma":[0.002166256,0.0003638321,0.0008415315,0.002529186,0.001011063,0.002417716,0.001225981,0.003740938,0.002148659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009872133,"about_ca_system_score_gemma":0.00144725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001274765,"about_ca_topic_score_gemma":0.001290663,"domain_scores_codex":[0.9993989,0.0001667544,0.00008918462,0.0000798875,0.0002188793,0.00004629808],"domain_scores_gemma":[0.9989176,0.0006726311,0.00009081794,0.00003266669,0.0002303333,0.00005602104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001042223,0.00007243783,0.0003277397,0.02175786,0.000154797,0.0002247629,0.0001155451,0.0003387297,0.001245806,0.009242564,0.02621039,0.9402052],"study_design_scores_gemma":[0.00001461963,0.000123602,0.0009055321,0.009499838,0.0001283522,0.001082382,0.0001206974,0.0001084226,0.0003797919,0.006088231,0.9815198,0.00002863793],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004655855,0.9986176,0.0001325952,0.0003662329,0.0002804584,0.000003450252,0.000009779692,0.000005526976,0.0005377205],"genre_scores_gemma":[0.0003999375,0.9985527,0.0002145668,0.0002602289,0.0002505869,0.000005845749,0.00001755692,0.000001626718,0.0002969009],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002912937,"threshold_uncertainty_score":0.009744763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06755764124624694,"score_gpt":0.326329138270564,"score_spread":0.2587714970243171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}